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Re: Pintura de cabeloFrom: Ricardo Savaris (savaris@orion.ufrgs.br)Sun, 28 Mar 1999 23:31:57 -0300
Aqui está um artigo sobre essa associacao, que apesar de usar uma quantidade muito superior ao utilizado normalmente, não demonstrou nenhuma associacao com teratogenicidade fetal TITLE: Teratology and percutaneous toxicity studies on hair dyes. AUTHORS: Burnett C; Goldenthal EI; Harris SB; Wazeter FX; Strausburg J; Kapp R; Voelker R SOURCE: J Toxicol Environ Health 1976 Jul;1(6):1027-40 CITATION IDS: PMID: 966314 UI: 77009076 ABSTRACT: Twelve hair dye formulations were tested for systemic toxicity by topical application twice weekly for 13 wk to groups of 12 New Zealand white rabbits and for teratologic effects following applications to groups of 20 pregnant Charles River CD rats on days 1, 4, 7, 10, 13, 16, and 19 of gestation. The three semipermanent formulations were applied as is, and the nine oxidation dyes were mixed 1:1 with 6% hydrogen peroxide just prior to application, as in normal use. The formulations induced a broad spectrum of dyes and dye intermediates used or considered useful in oxidative and semipermanent hair color products. In the teratology study no biologically significant soft tissue or skeletal changes were noted. Similarly, the mean numbers of corpora lutea, implantation sites, live fetuses, and resorptions per pregnancy, as well as numbers of litters with resporptions, were not significantly affected by the dye treatment. In the percutaneous toxicity study there was no evidence of compound-induced systemic effects. Microscopic examination of 25 tissues from each animal gave no indication of histomorphologic evidence of toxicity. No dye discoloration of urine was seen at any time during the test or at necropsy. Some of the dye groups showed epidermal hyperplasia, which was probably a reflection of slight irritation due to the frequency of application of the oxidation formulations. -----Mensagem original----- De: José Jacyr Leal Júnior <caf@jacyrleal.com.br> Para: Multiple recipients of list OBSTET-L <obstet-l@talk.obgyn.net> Data: Domingo, 28 de Março de 1999 22:10 Assunto: Pintura de cabelo Prezados colegas da lista Sempre soube que as gestantes não deveriam pintar o cabelo porque em muitos dos produtos utilizados poderiam existir substâncias como chumbo ou amonia etc... que poderiam trazer danos ao feto. Muitos colegas estão relaxando quanto a dar essa orientação muitas vezes mais por insistência da gestante. O que acham os colegas da lista e onde podemos encontrar trabalhos sérios sobre o assunto. Parece-me que existe inclusive uma relação com achados de tumores cerebrais nos fetos ??? Um abraço José Jacyr Leal Junior Centro de Avaliação Fetal Batel SC Ltda. Curitiba - Paraná caf@jacyrleal.com.br http://wwwjacyrleal.com.br
Voltar para Administrador da lista: flavio.monteiro.desouza@obgyn.net Solicitações à lista: obstet-l-request@obgyn.net Última atualização: Wed Mar 26 19:49:17 2008 |
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