trabalhos interessantes XIV

From: Jaime (jaimen@zaz.com.br)
Fri, 18 May 2001 23:13:25 -0300


Aos colegas da lista.

Os leiomiomas aumentam a pressão arterial. (?)

Numa primeira observação a Dra. Denise M. Elser de Illinois descobriu uma intrigante associação entre leiomiomas e hipertensão arterial e apresentou seus achados no 50th annual meeting of the American College of Obstetricians and Gynecologists, no último 02 de Maio. No estudo piloto ela chegou a encontrar diferenças estatísiticas bem significantes: 51.1% das mulheres com leiomiomas eram hipertensas contra 16,7% do grupo sem miomas.

Acredita a autora que essa curiosa associação estaria ligada a níveis de angiotensina II que seriam mais elevados ou por apresentarem defeitos. O próximo passo será estudar a possibilidade de tratar miomas com conversores de angiotensina II, afirma a autora. (?)

MAIS DETALHES:

Fibroids May Increase Risk of Hypertension ---------------------------------------------------------------------------- ---- ----------------------------------------------------------------------------

---------------------------------------------------------------------------- CHICAGO (Reuters Health) May 02 - The prevalence of hypertension appears to be higher among women with uterine leiomyomata than among women in the general US population.

In a pilot study, Dr. Denise M. Elser, from Christ Hospital and Medical Center in Oak Lawn, Illinois, and colleagues compared findings on 205 women diagnosed with uterine leiomyomata and with data on women who participated in the Third National Health and Nutrition Examination Survey (NHANES III), a US government survey.

In a poster presentation at the 50th annual meeting of the American College of Obstetricians and Gynecologists, Dr. Elser's group reported that, overall, 49% of the women with uterine leiomyomata were hypertensive compared with 18% of the women in NHANES III.

Among white women with uterine leiomyomata, 51.1% were hypertensive compared with 16.7% of women surveyed in NHANES III, and among African-American women, 50.8% with uterine leiomyomata were hypertensive compared with 28.1% of those surveyed in NHANES III.

"This association between fibroids and hypertension we believe is caused by angiotensin II levels which are too high or receptors which are faulty. Our next step is to study women's angiotensin II levels and see if we can treat fibroids with angiotensin-converting enzyme inhibitors," Dr. Elser told Reuters Health.

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     Jaime Nonato    http://www.geocities.com/jjndo    jaimen@zaz.com.br

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