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trabalhos interessantes XFrom: Jaime (jaimen@zaz.com.br)Wed, 28 Mar 2001 22:37:11 -0300
Aos colegas da lista Mulherese cegas ou parcialmente cegas têm menor risco de câncer de mama. Dr. J. Kliukiene e sua equipe, Noruega acompanharam 15.412 mulheres deficientes visuais, desde 1961 e descobriram que essas mulheres têm baixo risco para ca de mama. Isso reforça a "Hipótese da Melatonina": A luz visível diminui os niveis de Melatonina e os baixos níveis de Melatonina estariam associados a maior incidência de ca de mama. O trabalho foi publicado no British Journal of Cancer em 02 de fevereiro de 2001. Mais detalhes: Risk of Breast Cancer Decreased in Blind Women ---------------------------------------------------------------------------- ---- ---------------------------------------------------------------------------- ---------------------------------------------------------------------------- WESTPORT, CT (Reuters Health) Mar 09 - Research conducted in Norway indicates that totally blind women are at decreased risk for breast cancer, especially those who became blind before age 65 years. "Our findings give support to the 'melatonin hypothesis'," the researchers say, which postulates that melatonin has a protective effect against breast cancer. Dr. J. Kliukiene and colleagues, of the Cancer Registry of Norway, in Oslo, used data from the Norwegian Registry of Blindness to identify 15,412 visually impaired women. Of these, 396 were totally blind. Based on follow-up beginning in 1961 or at the onset of blindness, the standardized incidence ratio for breast cancer was 0.64 in totally blind women. For those blinded before age 65, the incidence ratio was 0.51, the investigators report in the British Journal of Cancer for February 2. There appeared to be no association between visual impairment short of total blindness and breast cancer, as illustrated by the standardized incidence ratio of 0.92 for those with moderate low vision and 1.21 for those with near-total blindness. According to the authors, experimental evidence shows that increased nocturnal exposure to visible light reduces melatonin levels and is associated with increased growth of breast cancer. Blind women who are not ocularly receptive to light may maintain melatonin production at night regardless of light exposure. Dr. Kliukiene's team suggests that this is the mechanism whereby these women are protected from breast cancer. Br J Cancer 2001;84:397-399.
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Jaime Nonato http://www.geocities.com/jjndo jaimen@zaz.com.br
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