Re: Nifedipina

From: ronniem@vtr.net
Thu Jan 30 12:48:39 2003


...estimados colegas

...creo debemos esperar series mas grandes, por el momento deberia usarse el betamimetico como droga de primera eleccion...obviamente por via E.V y solamente en espera de lograr efecto de corticoides ( ninguna indicacion por via oral)

...emulando a stephen con su frase sobre el Universo...."el parto prematuro solo es ">-

ronnie

- Mensaje Original -- >Date: Thu, 30 Jan 2003 04:18:27 -0600
>Reply-To: obgin-l@obgyn.net
>From: J.Bartha@bristol.ac.uk (Jose Luis)
>To: Multiple recipients of list OBGIN-L <obgin-l@mail.medispecialty.com>
>Subject: Re: Nifedipina
>
>Estimado Carlos,
>
>He intentado un par de veces enviarte e-mail pero no he podido. Me los
>devuelven diciendo que no tienes suficiente sitio en tu "mail box". La
>primera vez te mandaba la revisión Cochrane completa y la segunda vez
>solo la referencia para que ocupara menos espacio. Ningua de las dos
>veces tuvo éxito, lo siento.
>Referente a la dosis, lo habitual es emplear 10 mg cada 10-20 minutos
>hasta un máximo de 30 mg como dosis de ataque. Hay quien da los 30 mg
>juntos pero a mi modo de ver (esto es una apreciación subjetiva) produce
>má hipotensiones, dolores de cabeza y "flushes". Después como
>mantenimiento puedes usar entre 60 y 120 mg al día repartidos entre 3
>tomas (1-2 cps del preparado retard (contiene 20 mg)cada 8 horas).
>
>Los estudios incluidos en la revisión Cochrane son los siguientes:
>
>References to studies included in this review
>
>Bracero 1991 (published data only)
>
>Bracero LA, Leiken E, Kirshenbaum N, Tejani N. Comparison of nifedipine
>and ritodrine for the treatment of preterm labor. Proceedings of 10th
>Annual Meeting of Society of Perinatal Obstetricians; 1990; Houston,
>Texas, USA, 1990:77.Bracero LA, Leikin E, Kirshenbaum N, Tejani N.
>Comparison of nifedipine and ritodrine for the treatment of preterm
>labor. American Journal of Perinatology 1991;8(6):365-9. [Context
>Link]
>
>Ferguson 1990 (published data only)
>
>Ferguson JE, Dyson DC, Holbrook RH Jr, Schultz T, Stevenson DK.
>Cardiovascular and metabolic effects associated with nifedipine and
>ritodrine tocolysis. American Journal of Obstetrics and Gynecology
>1989;161(3):788-95.Ferguson JE, Dyson DC, Schutz T, Stevenson DK. A
>comparison of tocolysis with nifedipine or ritodrine: analysis of
>efficacy and maternal, fetal, and neonatal outcome. American Journal of
>Obstetrics and Gynecology 1990;163(1 Pt 1):105-11.Ferguson JE, Schultz
>TE, Stevenson DK. Neonatal bilirubin production after preterm labor
>tocolysis with nifedipine. Developmental Pharmacology Therapeutics
>1989;12(3):113-7. [Context Link]
>
>Garcia-Velasco 1998 (published data only)
>
>Garcia-Velasco JA, Gonzalez Gonzalez A. A prospective, randomized trial
>of nifedipine vs. ritodrine in threatened preterm labor. International
>Journal of Gynaecology and Obstetrics 1998;61:239-44. [Context Link]
>
>Glock 1993 (published data only)
>
>Glock JL, Morales WJ. Efficacy and safety of nifedipine vs magnesium
>sulfate in the management of preterm labor: a randomized study. American
>Journal of Obstetrics and Gynecology 1993;169(4):960-4.Morales WJ, Glock
>D. Efficacy and safety of nifedipine vs magnesium sulfate in the
>management of preterm labor: a randomized study. American Journal of
>Obstetrics and Gynecology 1993;168:375.
>
>Janky 1990 (published data only)
>
>Janky E, Leng JJ, Cormier PH, Salamon R, Meynard J. A randomized study
>of the treatment of threatened premature labor. Nifedipine versus
>ritodrine. Journal de Gynecologie, Obstetrique et Biologie de la
>Reproduction (Paris) 1990;19:478-82. [Context Link]
>
>Jannet 1997 (published data only)
>
>Jannet D, Abankwa A, Guyard B, Carbonne B, Marpeau L, Milliez J.
>Nicardipine versus salbutamol in the treatment of premature labor. A
>prospective randomized study. European Journal of Obstetrics,
>Gynecology and Reproductive Biology 1997;73(1):11-6. [Context Link]
>
>Koks 1998 (published data only)
>
>Koks CA, Brolmann HA, de Kleine MJ, Manger PA. A randomized comparison
>of nifedipine and ritodrine for suppression of preterm labor. European
>Journal of Obstetrics, Gynecology and Reproductive Biology
>1998;77(2):171-6. [Context Link]
>
>Kupferminc 1993 (published data only)
>
>Kupferminc M, Lessing JB, Peyser MR. A comparative, prospective,
>randomized study of nifedipine vs ritodrine for suppressing preterm
>labor. Proceedings of 39th Annual Meeting of the Society for
>Gynecologic Investigation; 1992; San Antonio, Texas, USA,
>1992:335.Kupferminc M, Lessing JB, Yaron Y, Peyser MR. Nifedipine
>versus ritodrine for suppression of preterm labour. British Journal of
>Obstetrics and Gynaecology 1993;100(12):1090-4. [Context Link]
>
>Larmon 1999 (published data only)
>
>Larmon J, Ross B, May W, Dickerson G, Fischer R, Morrison JC. Oral
>nicardipine versus intravenous magnesium sulfate for the treatment of
>pretem labor. American Journal of Obstetrics and Gynecology
>1999;181:1432-7. [Context Link]
>
>Papatsonis 1997 (published data only)
>
>Papatsonis DN, Kok JH, van Geijn HP, Bleker OP, Ader HJ, Dekker GA.
>Neonatal effects of nifedipine and ritodrine for preterm labor.
>Obstetrics and Gynecology 2000;95(4):477-81.Papatsonis DN, van Geijn HP,
>Ader HJ, Lange FM, Bleker OP, Dekker GA. Nifedipine and ritodrine in
>the management of preterm labor: a randomized multicenter trial.
>Obstetrics and Gynecology 1997;90(2):230-4.Papatsonis DN, van Geijn HP,
>Ader HJ, Lange FM, Bleker OP, Dekker GA. Tocolytic efficacy of
>nifedipine versus ritodrine; results of a randomized trial. American
>Journal of Obstetrics and Gynecology 1996;174:306.Papatsonis DNM, Kok
>JH, Samson JF, Lange FM, Ader HJ, Dekker GA. Neonatal morbidity after
>randomised trial comparing nifedipine with ritodrine in the managment of
>preterm labor. American Journal of Obstetrics and Gynecology
>1997;176(1):S117.Papatsonis DNM, Kok JH, van Geijin HP, Bleker OP, Ader
>HJ, Dekker GA. Neonatal effects of nifedipine and ritodrine in the
>management of preterm labor. Proceedings of the 5th Annual Congress of
>the Perinatal Society of Australia and New Zealand; 2001 March;
>Canberra, Australia, 2001:100.Papatsonis DNM, van Geijin HP, Kok JH,
>Ader HJ, Dekker GA. Adjuvant use of indomethacin for preterm labor: is
>it safe to use? Proceedings of the 5th Annual Congress of the Perinatal
>Society of Australia and New Zealand; 2001 March; Canberra, Australia,
>2001:296.Papatsonis DNM, van Geijn HP, Dekker GA. Nifedipine as a safe
>and effective tocolytic agent in the treatment of preterm labor
>(letter). American Journal of Obstetrics and Gynecology 2000;183:513.
>[Context Link]
>
>Read 1986 (published data only)
>Read MD, Wellby DE. The use of a calcium antagonist (nifedipine) to
>suppress preterm labour. British Journal of Obstetrics and Gynaecology
>1986;93(9):933-7. [Context Link]
>
>Espero que te sea de utilidad.
>
>Saludos
>
>José Luis
>
>At Wed, 29 Jan 2003, Carlos Brito wrote:
>>
>>At Wed, 29 Jan 2003, Dr. Fco. Javier Robles Elias wrote:
>>>
>>>Dr. Jose Luis
>>>
>>>Seria usted tan amable de enviarme la referenica especifica donde se
senala >>>la superiodad de nifedipina, dosis etc.
>>>
>>anoteme en la lista, saludos.
>>
>>--
>>Cada vez que logro ver mis incontables imperfecciones y defectos me llego
>a sentir menos imperfecto
>>
>


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