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Re: Nifedipina
From: Jose Luis (J.Bartha@bristol.ac.uk)
Thu Jan 30 03:15:36 2003
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Estimado Carlos,He intentado un par de veces enviarte e-mail pero no he podido. Me los devuelven diciendo que no tienes suficiente sitio en tu "mail box". La primera vez te mandaba la revisión Cochrane completa y la segunda vez solo la referencia para que ocupara menos espacio. Ningua de las dos veces tuvo éxito, lo siento. Referente a la dosis, lo habitual es emplear 10 mg cada 10-20 minutos hasta un máximo de 30 mg como dosis de ataque. Hay quien da los 30 mg juntos pero a mi modo de ver (esto es una apreciación subjetiva) produce má hipotensiones, dolores de cabeza y "flushes". Después como mantenimiento puedes usar entre 60 y 120 mg al día repartidos entre 3 tomas (1-2 cps del preparado retard (contiene 20 mg)cada 8 horas).
Los estudios incluidos en la revisión Cochrane son los siguientes:
References to studies included in this review
Bracero 1991 (published data only)
Bracero LA, Leiken E, Kirshenbaum N, Tejani N. Comparison of nifedipine and ritodrine for the treatment of preterm labor. Proceedings of 10th Annual Meeting of Society of Perinatal Obstetricians; 1990; Houston, Texas, USA, 1990:77.Bracero LA, Leikin E, Kirshenbaum N, Tejani N. Comparison of nifedipine and ritodrine for the treatment of preterm labor. American Journal of Perinatology 1991;8(6):365-9. [Context Link]
Ferguson 1990 (published data only)
Ferguson JE, Dyson DC, Holbrook RH Jr, Schultz T, Stevenson DK. Cardiovascular and metabolic effects associated with nifedipine and ritodrine tocolysis. American Journal of Obstetrics and Gynecology 1989;161(3):788-95.Ferguson JE, Dyson DC, Schutz T, Stevenson DK. A comparison of tocolysis with nifedipine or ritodrine: analysis of efficacy and maternal, fetal, and neonatal outcome. American Journal of Obstetrics and Gynecology 1990;163(1 Pt 1):105-11.Ferguson JE, Schultz TE, Stevenson DK. Neonatal bilirubin production after preterm labor tocolysis with nifedipine. Developmental Pharmacology Therapeutics 1989;12(3):113-7. [Context Link]
Garcia-Velasco 1998 (published data only)
Garcia-Velasco JA, Gonzalez Gonzalez A. A prospective, randomized trial of nifedipine vs. ritodrine in threatened preterm labor. International Journal of Gynaecology and Obstetrics 1998;61:239-44. [Context Link]
Glock 1993 (published data only)
Glock JL, Morales WJ. Efficacy and safety of nifedipine vs magnesium sulfate in the management of preterm labor: a randomized study. American Journal of Obstetrics and Gynecology 1993;169(4):960-4.Morales WJ, Glock D. Efficacy and safety of nifedipine vs magnesium sulfate in the management of preterm labor: a randomized study. American Journal of Obstetrics and Gynecology 1993;168:375.
Janky 1990 (published data only)
Janky E, Leng JJ, Cormier PH, Salamon R, Meynard J. A randomized study of the treatment of threatened premature labor. Nifedipine versus ritodrine. Journal de Gynecologie, Obstetrique et Biologie de la Reproduction (Paris) 1990;19:478-82. [Context Link]
Jannet 1997 (published data only)
Jannet D, Abankwa A, Guyard B, Carbonne B, Marpeau L, Milliez J. Nicardipine versus salbutamol in the treatment of premature labor. A prospective randomized study. European Journal of Obstetrics, Gynecology and Reproductive Biology 1997;73(1):11-6. [Context Link]
Koks 1998 (published data only)
Koks CA, Brolmann HA, de Kleine MJ, Manger PA. A randomized comparison of nifedipine and ritodrine for suppression of preterm labor. European Journal of Obstetrics, Gynecology and Reproductive Biology 1998;77(2):171-6. [Context Link]
Kupferminc 1993 (published data only)
Kupferminc M, Lessing JB, Peyser MR. A comparative, prospective, randomized study of nifedipine vs ritodrine for suppressing preterm labor. Proceedings of 39th Annual Meeting of the Society for Gynecologic Investigation; 1992; San Antonio, Texas, USA, 1992:335.Kupferminc M, Lessing JB, Yaron Y, Peyser MR. Nifedipine versus ritodrine for suppression of preterm labour. British Journal of Obstetrics and Gynaecology 1993;100(12):1090-4. [Context Link]
Larmon 1999 (published data only)
Larmon J, Ross B, May W, Dickerson G, Fischer R, Morrison JC. Oral nicardipine versus intravenous magnesium sulfate for the treatment of pretem labor. American Journal of Obstetrics and Gynecology 1999;181:1432-7. [Context Link]
Papatsonis 1997 (published data only)
Papatsonis DN, Kok JH, van Geijn HP, Bleker OP, Ader HJ, Dekker GA. Neonatal effects of nifedipine and ritodrine for preterm labor. Obstetrics and Gynecology 2000;95(4):477-81.Papatsonis DN, van Geijn HP, Ader HJ, Lange FM, Bleker OP, Dekker GA. Nifedipine and ritodrine in the management of preterm labor: a randomized multicenter trial. Obstetrics and Gynecology 1997;90(2):230-4.Papatsonis DN, van Geijn HP, Ader HJ, Lange FM, Bleker OP, Dekker GA. Tocolytic efficacy of nifedipine versus ritodrine; results of a randomized trial. American Journal of Obstetrics and Gynecology 1996;174:306.Papatsonis DNM, Kok JH, Samson JF, Lange FM, Ader HJ, Dekker GA. Neonatal morbidity after randomised trial comparing nifedipine with ritodrine in the managment of preterm labor. American Journal of Obstetrics and Gynecology 1997;176(1):S117.Papatsonis DNM, Kok JH, van Geijin HP, Bleker OP, Ader HJ, Dekker GA. Neonatal effects of nifedipine and ritodrine in the management of preterm labor. Proceedings of the 5th Annual Congress of the Perinatal Society of Australia and New Zealand; 2001 March; Canberra, Australia, 2001:100.Papatsonis DNM, van Geijin HP, Kok JH, Ader HJ, Dekker GA. Adjuvant use of indomethacin for preterm labor: is it safe to use? Proceedings of the 5th Annual Congress of the Perinatal Society of Australia and New Zealand; 2001 March; Canberra, Australia, 2001:296.Papatsonis DNM, van Geijn HP, Dekker GA. Nifedipine as a safe and effective tocolytic agent in the treatment of preterm labor (letter). American Journal of Obstetrics and Gynecology 2000;183:513. [Context Link]
Read 1986 (published data only) Read MD, Wellby DE. The use of a calcium antagonist (nifedipine) to suppress preterm labour. British Journal of Obstetrics and Gynaecology 1986;93(9):933-7. [Context Link]
Espero que te sea de utilidad.
Saludos
José Luis
At Wed, 29 Jan 2003, Carlos Brito wrote: >
>At Wed, 29 Jan 2003, Dr. Fco. Javier Robles Elias wrote:
>>
>>Dr. Jose Luis
>>
>>Seria usted tan amable de enviarme la referenica especifica donde se senala
>>la superiodad de nifedipina, dosis etc.
>>
>anoteme en la lista, saludos.
>
>--
>Cada vez que logro ver mis incontables imperfecciones y defectos me llego a sentir menos imperfecto
>
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