Re: hormone replacement and s/p tah bso

From: Dib Abdalla Chacur (chacur@rol.com.br)
Tue Oct 26 20:01:11 1999


1 - HRT does not increase the Relative Risk of breast cancer during five years of use 2 - The relative risk of breast cancer increases to 1,1( 1,2) after ten years use, but the benefits ( osteoporosis, cardiovascular disease, etc ) are greater than this increasing in Relative Risk 3 - After fifteen years the Relative Risk increases up to 1,4. In this late situation the increasing of the RR is important ( it is difficult to find a woman that has made HRT for such long time) 4 - Progesterone does not protect breast tissue, then why use it when a patient underwent to TAH/BSO ? 5 - Exist several papers about the subjects above medical literature . Best regards Dib

Jomyrwhipt@aol.com wrote:

> I was just precepting a Family Practice Resident and the woman presented for another complaint. In the presentation, the resident mentioned that this pt was s/p tah/bso and was taking prem-pro. I was under the impression and teaching that if you didn't have your uterus, then progesterone wasn't indicated. The resident, however, mentioned that the unopposed estrogen would increase the patients risk for breast cancer. I have two questions for the list.
>
> 1. What does the latest date suggest on unopposed Estrogen in a post-menopausal woman with tah/bso, and no family history of breast ca and no other risk factors, in increasing her risk for breast ca?
> 2. Is replacement of progesterone in a woman without a uterus necessary for other reasons, physiologically.
>
> I appreciate responses and articles to support your feedback would be helpful.
>
> Thanks,
>
> A. Todd Miller, MD
> Maternity Care Coordinator
> Columbia University Dept of Family Medicine

--
DIB ABDALLA CHACUR
Gynecology - Mastology
Teacher of Gynecology and Head of Gynecology and Obstetrics Dpto.
CAMPOS SCHOOL OF MEDICINE
Campos - RJ - Brazil

chacur@rol.com.br

Rua Barão de Miracema, 237 Fone (024) 7231759 Campos, RJ Brazil CEP 28.030-360

CLÍNICA FEMINA Rua Ovidio Manhães,127 Fone (024) 7332424 Fax (024) 7330361 Campos, RJ Brazil





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