Re: Abnormal smear post radiotx for Ca Cervix

From: Sejfulah Perva (pervaans@bih.net.ba)
Wed Oct 13 17:04:59 1999


At Sat, 02 Oct 1999, A.C. Evans wrote: >
>On Fri, 1 Oct 1999 09:42:52 -0500, mstmy@tm.net.my (John Teo) wrote:
>
>>I have a 61 years old patient who was diagnosed with squamous cell
>>carcinoma of the cervix stage 1b bulky and was treated with radiotherapy
>>in 1997. She remained well on follow up and asymptomatic.Routine follow
>>up pap smear currently was reported as "Atrophic smear showing marked
>>post radiation changes with a few groups of rather degenerate malignant
>>cells, highly suspicious of recurrence."
>>On examination the vaginal wall are adherent and plastered together
>>anteriorly and posteriorly.The cervix can`t be visualised at all. There
>>was however no obvious growth.
>
>Where was the Pap from, then?
>
>>My Question is what is the next course of action in confirming the
>>suspicion of recurrence?
>
>Send to a gyn oncologist.
>
>>1) Will a colposcopy be adequate in confirming or refuting the
>>diagnosis?
>
>No.
>
>>2)Or instead will a examination under anaesthesia be better to break
>>down the adhesions and attempt made to examine the cervix and if
>>necessary a biopsy performed?
>
>Yes. Needs Tru-Cut needle biopsies and perhaps laparoscopy.
>
>>3)What is the role of CT scan in the diagnosis of recurrences?
>
>Not good, but it is a reasonable test to evaluate extent of disease.
>That is, to evaluate for hydroureter or adenopathy or liver mets. I
>also get MRI if planning an exenteration to look for sidewall
>invasion.
>
>She needs prompt evaluation because she may be a candidate for
>exenterative (curative) surgery. Don't delay.
>
>Craig Evans, MD, PhD
>Director, Gynecologic Oncology
>Vince Lombardi Cancer Clinic
>Milwaukee, WI




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