Re: breast cancer in pregnant women

From: Gail Waldby (gwaldby@willinet.net)
Wed Oct 13 11:21:39 1999


I usually and I think this is the common approach in the US, only resect the apparently involved pectoralis muscle with an adequate rim of apparently normal muscle, instead of removing the entire pectoral muscles.

Chemotherapy has been given during pregnancy, except I think for alkylating agents, which are contraindicated. (I may have the wrong agent here, so check this.) Of course, there may always be effects on the baby, but it is within the standard of care to give chemo needed by the mother, except for the class of agents above.

For a better discussion of these issues, see Bland and Copeland's 2 volume set of Breast Cancer books published last year or early this year--wel worth reading--I just finished them this summer. Gail Waldby, MD Huron Clinic SD

Dib Abdalla Chacur wrote: >
> Gabriela Torres Cerino wrote:
>
> > Nice to meet you: My name is Gabriela Torres Cerino,I'm argentine, I'm
> > 26 and I got my degree in medicine last year.
> > I contact you because I'm writting a monography about breast cancer in
> > pregnant women and I would apreciate any help from you.
> > Sorry if my request is not formal but this is the first time I do this.
> > Thank you.
> > Dr. Torres Cerino.
>
> Dear colleague Gabriela,
>
> 1. I had15 days ago a patient with breast cancer, 35 y. o., with 16 weeks
> of pregnacy. It was a T3N1M0 ( stage III ).
>
> 2. In stage III I usually do Qt pre-op., after that I do a radical modified
> mastectomy (Patey ), and after the surgery Qt again and Irradiation.
>
> 3. In this case I have decided to do first surgery( during the surgery I
> saw that the tumor infiltrated the pectoralis major, and then I had to do a
> Halsted surgery). Macroscopically there was several axillar linfonodes with
> metastasis.
> I did not receive yet the histopathology.
>
> 4. The pregnancy, BY ITSELF, does not worsen the prognostic of breast
> cancer. In fact, these cases have a bad prognostic due the age of the
> patient. As you know, in this age breast cancer is more agressive, and has
> bad prognostic factors.
>
> 5. I will talk with the patient about Qt in third trimester.
>
> What is your opinion?
> Do you agree with me?
> What think the members of the list ?
> Best regards
> Dib
>
> --
> DIB ABDALLA CHACUR
> Gynecology - Mastology
> Teacher of Gynecology and Head of Gynecology and Obstetrics Dpto.
> CAMPOS SCHOOL OF MEDICINE
> Campos - RJ - Brazil
>
> chacur@rol.com.br
>
> Rua Barão de Miracema, 237
> Fone (024) 7231759
> Campos, RJ
> Brazil
> CEP 28.030-360
>
> CLÍNICA FEMINA
> Rua Ovidio Manhães,127
> Fone (024) 7332424
> Fax (024) 7330361
> Campos, RJ
> Brazil





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