Re: A case of sterility

From: Steve (Steve@dhngwe2.db.healthlink.org.za)
Mon Oct 11 15:46:16 1999


The reason why progesterone levels are measured in investigating fertility is that the follicle doesn't luteinise until LH (Luteotropic Hormone) surges to produce ovulation. Without the LH surge there is no ovulation and without ovulation there is no progesterone production because the follicle doesn't luteinise. It is possible to have an "unruptured luteinised follicle" (so-called) but these are rare. I have always believed that ovulation is an esssential prerequisite for progesterone production.

> From: "Jeffrey W. Clemens" <clemens@duq.edu>
>
> Steve,
>
> Wouldn't progesterone levels prove luteinization and not ovulation?
>
> Jeff
> --
> Jeffrey W. Clemens, Ph.D.
> Assistant Professor, Biological Sciences
> Duquesne University
> Pittsburgh, PA 15282
> 412-396-4597
> fax-5907
> http://www.home.cc.duq.edu/~clemens/
> ----------
> >>> 36 y.o. sterile woman, normal patency of the fallopian tubes, normal
> >> spermogramme.
> >>...
> >> Progesterone - 53 (25-87 nmom/l) day 20
> >> Estradiol 1250 (176-885 pmol/l) day 20
> >> Prolactin - 545 (78-580 mmol/l) day 20
> >>
> > The Progesterone level on day 20 proves ovulation despite what your temp
> charts

Steve Raymond Head of O & G Empangeni Hospital SOUTH AFRICA





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