Re: doxycicline usage in pregnancy

From: DoctorJoe@aol.com
Wed Aug 25 13:13:23 1999


In a message dated 8/25/99 10:09:52 AM, nisa@unimedya.net.tr writes:

<< We have patient, G4P1A2, 35 yo, 12 wks in this pregnancy. Normal appearence in US. NT 1.1 mm. She was used doxycicline 1 capsule each day between 22nd and 44 th postmenstrual days. The family is very anixous for the potential teratogenic effects of the drug. They want advice about termination or continuation of pregnancy. Any comment? Thanks in advance. >>

I think out of all the "usual" tetracyclines, doxycycline is one of the least likely to cross the placenta and hasn't been yet demonstrated to cause fetopathy, to my understanding. Also, one capsule daily is half the usual dose, so blood levels would be relatively low.

Joe P.





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