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Re: Persistent hot flashes.From: Dan Logen (pdl@whidbey.net)Tue Aug 17 21:50:48 1999
The estradiol level of 156 shows that she doesn't need more estrogen. I doubt that a different product will help. When was the estradiol drawn with reference to ingestion of the estrogen? I usually have it drawn at about 8 hours. If this was an early morning level just prior to next dose, she actually may be getting too much estrogen. I have had one patient that paradoxically felt better when she lowered her estrogen replacement down to a level which gave her an estradiol in the therapeutic level (50-150). She had been at around 350 and still had hot flashes. Another thought is to have her take her estrogen at bedtime. This might give her higher levels at night. Also might consider measuring serum Testosterone and DHEA-s levels and replacing if low. I'm not sure that these are connected to hot flashes, but replacement may improve general well being if they are documented low.
-- Dan Logen Private Practice OB-GYN Mt. Vernon, WA
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