Re: microinvasive adenoca of the endocervix - does this really exist?? was: Atypical Endocervical Cells--followup

From: Anthony Evans (ahcevans@execpc.com)
Thu May 13 07:43:57 1999


On Wed, 12 May 1999 19:19:54 -0500, pprior@earthlink.net (Paul Prior MD) wrote:

>
>A hotly debated subject, and one i have current interest in as I just
>got back a colpo biopsy report stating adenoca of the endocervix
>in-situ (pap was AGCUS).
>
>Is there really such a beast? Is a cone really adequate? I'm not so
>sure this has been answered to the degree squamous lesions have.

There is no such thing as microinvasive adenocarcinoma. Any invasion needs treatment with radical hysterectomy/nodes or radiation therapy.

LEEP specimen margins are positive in 50% of patients with cervical adenocarcinoma in situ (vs 33% with CKC). Among women with adenoca in situ who don't have a hysterectomy, 6% of those treated with CKC will recur while 29% of those managed with LEEP will. These are the reasons that CKC is the preferred method of managing patients with primary glandular lesions. Many pathologists think that CKC is easier to evaluate for invasion as well.

Craig Evans, M.D., Ph.D. Vince Lombardi Cancer Clinic Milwaukee, WI





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