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Ethnicity!From: Bert Gold (bgold@ktb.net)Thu Apr 29 22:26:24 1999
Kind doctors, I am currently substituting for the Director of SB's Genetic Testing Center, while she is away. In the course of signing and composing genetics reports, I am finding many test requests where physicians have asked for a detailed molecular work-up, often on a pregnant patient, without supplying ethnicity data. Geneticists, as I'm certain you will all remember, are kind of obsessed with ethnic divisions insofar as these affect gene frequencies in intermarrying populations. Which is to say, it really IS important for me to know whether the Cystic Fibrosis gene screen you've requested is being conducted on an Ashkenazi jew, an African American or an Asian woman (or man). Detection frequencies vary in each of these populations according to ethnicity. So, please try and fill out these bothersome forms we geneticists supply you with in some detail. For it really does affect your AFP and AFP plus results, your CF carrier test results (and prenatal diagnostics), all of the Jewish Ashkenazi screens you guys do (Tay-Sachs, Canavans and Gaucher's disease) etc. My colleagues at academic and commercial labs. all around the country will much appreciate your help. -- ##########################################################
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