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Re: placebo effects From: Jeffrey W. Clemens (clemens@duq.edu) Thu Apr 15 07:53:47 1999 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Geffrey Klein: "Re: Naturally" Previous message: Robert J. Woolley: "Re: OB-GYN-L digest 356" Dear Listers, Check out the 9 April, '99 issue of Science for an interesting discussion of placebo effects (p. 238 in News Focus section). Online (unsure of access limits for non-subscribers) at http://www.sciencemag.org OR http://www.scienceonline,org OR http://www.sciencenow.org). As cited in the article, a peer-reviewed meta-analysis claimed that 3/4 of many anti-depressant's effectiveness are due to a placebo effect (Prevention and Treatment, online @ journals.apa.org/prevention. Food for thought. One way discussed in the article to eliminate placebo effects in studies is to lie to trial participants by telling people they are not getting the drug when they really are. So design is an "unblinded" placebo and a drug group. Each group then divided into a "real" placebo or drug sub-group. This design could "make it possible to find out what a drug does when people think they are not getting it". Presents a bit of a problem with informed consent though. Jeff Jeffrey W. Clemens, Ph.D. Assistant Professor, Dept. of Biological Sciences Duquesne University Pittsburgh, PA 15282 412-396-4597 Fax-5907 >>it must be mass hysteria or >> placebo effect. >> I did just now take my first EVISTA tablet. That European study that >> demonstrated 54% decrease in breast cancer impressed me. > >What, please, is an "RT" and a "RDMS"? Bob, please resist an ad hominen urge >Do you propose that we decide on the efficacy of treatments based on anecdotes >over the "scientific studies" you denounce? > >Do you deny that a large number of people experiencing subjective improvement >after some treatment is instituted could be experiencing a placebo effect? >Bob Woolley >St. Paul, Minnesota Next message: Geffrey Klein: "Re: Naturally" Previous message: Robert J. Woolley: "Re: OB-GYN-L digest 356"

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