Re: gynecologic oncologists

From: Geffrey H. Klein, MD (gklein@icsi.net)
Tue Mar 30 21:19:45 1999


At 7:20 PM -0600 on 3/30/99, Robin wrote:

> The following is an excerpt from the NIH Consensus Development
> Conference Statement, April 5-7, 1994:
>
> "Women with ovarian masses who have been identified preoperatively as
> having a significant risk of ovarian cancer should be given the option
> of having their surgery performed by a gynecologic oncologist"

Since you are preaching to us, you must be familiar with this month's Green Journal article regarding this issue..

--
_________

The risk-of-malignancy index to evaluate potential ovarian cancers in local hospitals

Solveig Tingulstad, MD, Bjørn Hagen, MD, PhD, Finn Egil Skjeldestad, MD, PhD, Tore Halvorsen, MD, PhD, Kjell Nustad, MD, PhD, and Mathias Onsrud, MD, PhD

Objective: To assess the risk-of-malignancy index (a scoring system based on menopausal status, ultrasound features, and serum CA 125) at district hospitals for referral of women with suspected malignant pelvic masses for primary surgery at a central gynecologic oncology unit.

Methods: All seven hospitals in Health Region IV, Norway, agreed to refer women with pelvic masses and risk-of-malignancy indices of 200 or more for centralized primary surgery. In total, 365 women 30 years of age or older, admitted consecutively at the local hospitals, were enrolled in the study from February 1, 1995, to January 31, 1997.

Results: Compliance with the study was satisfactory; 84% (65 of 77) of women with risk-of-malignancy indices of at least 200 were referred for centralized primary surgery. Sensitivity and specificity to malignancy were 71% and 92%, respectively, which is in agreement with previous validation of the risk-of-malignancy index in teaching hospital settings. False negatives were due mainly to stage Ia (18 of 24) ovarian cancer, whereas 27 of 28 stage II-IV ovarian cancer cases were identified correctly.

Conclusion: The risk-of-malignancy index identified women with malignant pelvic masses efficiently. Our study showed the risk-of-malignancy index strategy in a practical setting to be able to centralize primary surgery for advanced ovarian cancer from local hospitals to a subspecialty unit. We recommend the risk-of-malignancy index for detection of patients with advanced ovarian cancer for centralized primary surgery.

(Obstet Gynecol 1999;93:448-452. © 1999 by The American College of Obstetricians and Gynecologists.)

Department of Obstetrics and Gynecology, University Hospital of Trondheim, Trondheim, Norway Department of Pathology, University Hospital of Trondheim, Trondheim, Norway Section of Epidemiological Research, SINTEF, UNIMED, Trondheim, Norway Central Laboratory, The Norwegian Radium Hospital, Oslo, Norway

Geffrey H. Klein, MD geffrey.klein@obgyn.net 2200 Nasa Rd 1 #200 Houston, Texas 77058 (713) 741 2273 ext 2628





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