Advice on normal serum AFP, elevated amniotic fluid AFP?
From: annette lee (aleeoc@rocketmail.com)
Thu Mar 25 11:23:10 1999
How would you manage a patient with a normal triple
screen who underwent genetic amnio at 16 weeks (well
dated by LMP and first trimester sono) and was found
to have nl 46XY karyotype but AMNIOTIC fluid AFP 2.1 MOM. Amniotic fluid negative for fetal hemaglobin
ruling out contamination with fetal blood.
Acetylcholinesterase negative and no evidence of
renal, neural tube or GI abnormality on level 2 scan?
A quick medline search suggests that this is either a
false positive, could indicate increased risk of
pre-eclampsia or very subtle neural tube defect. The
patient is a physician to boot.
|
|
