Re: Cytotec induction/ripening -timing

From: Efrain Ramirez MD (eramirez@icepr.com)
Sat Jan 9 09:51:55 1999


Luis ..have you found that the action of intravaginal cytotec is sometimes erratical? It seems to me that if the patient has some type of vagintis (yeast, BV) Cytotec does not work properly..in those situations I am willing to try and use PO..what are your thoghts? At Sat, 9 Jan 1999, Luis Sanchez-Ramos wrote: >
>At Sat, 9 Jan 1999, Douglas Krell MD wrote:
>>>The use of the 100 mcg oral dose makes sense given the recent literature<<
>
>I agree with you. The oral dose for misoprostol as a labor induction
>agent is somewhere between 100 and 200 micrograms. The studies using
>smaller doses have not shown great efficacy. Personally, I see no
>benefit for the oral route. Smaller doses administered intravaginally
>work very well. The only advantage of using the oral route would be for
>outpatient use (which is not safe or recommended). One advantage of
>vagianl administration is easy removal in cases of marked tachysytole
>and/or hyperstimulation.
>
>--
>Luis Sanchez-Ramos, MD
>

--
Efrain Ramirez MD FACOG




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