Re: OB: Clark et al

From: Pat Sonnenstuhl (webmidwife1@home.com)
Thu Dec 31 18:41:54 1998


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Does the article state when the epidural was given, especially to the nullips? That is the most significant factor IMHO. Occasionally, it's essential for the nullip who is having a difficult time. I like to wait until 3+ cms....

Geffrey Klein wrote: >
> Reference: Clark et al. The influence of epidural analgesia on cesarean
> delivery rates: A randomized, prospective clinical trial. Am J Obstet
> Gynecol 1998;179:1527-33.
>
> This is a good article. It refutes any increased risk of cesarean from
> epidural in nulliparous patients.
>
> Interesting facts from the study include:
>
> 1) total cesarean rate was very low for both epidural and meperidine
> groups (intention to treat analysis). 9% epidural vs 13% demerol.
> 2) active mgmt of labor protocol was used and pitocin was used often
> (70% of cases)
> 3) more than half of the women randomized to IV narcotic crossed over to
> epidural. despite this, allocation compliant analysis showed cesarean
> rates of 8% for epidural and 7% for IV narcotic.
> 4) the patient population under the age of 18 was more than half of the
> patients
> 5) They had a significant number of babies with arterial cord pH under
> 7.15. (allocation compliant analysis: 8% epidural arm vs 26% in opiod
> group)
>
> I take away from this study that if nulliparous labor is aggressively
> managed that cesarean rates are low and there is no added effect from
> epidural to increase the cesarean rate.
>
> Any comments on this interesting study?
>
> Geffrey H Klein, MD
> Dept OB-GYN
> MacGregor Medical Association
> 2200 Nasa Road 1 Suite 200
> Houston, Texas 77058
> (713) 741-2273 ext. 2628
> geffrey.klein@obgyn.net





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