The American Journal of Obstetrics and Gynecology, 8/98

From: brent.bailey@mosby.com
Mon Aug 31 18:10:57 1998


[note: for a unspecified limited time Mosby's is placing the full text version of AJOG on the Internet for free. FYI - Bruce]
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The American Journal of Obstetrics and Gynecology Table of Contents for August 1998, Volume 179, Number 2 http://www.mosby.com/ajog

Neonatal mortality for very low birth weight deliveries in South Carolina by level of hospital perinatal service M. Kathryn Menard, MD, MPH, Qiduan Liu, PhD, Elin A. Holgren, CNM, MPH, William M. Sappenfield, MD, MPH Charleston and Columbia, South Carolina, and Atlanta, Georgia Neonatal mortality among very-low-birth-weight infants was significantly lower for deliveries at level III hospitals in South Carolina than at level I or level II hospitals or at level II hospitals with neonatologists.

Atypical glandular cells of undetermined significance: A five-year retrospective histopathologic study Dan S. Veljovich, MD, Mark H. Stoler, MD, Willie A. Andersen, MD, Jamie L. Covell, BS, CT(ASCP), Laurel W. Rice, MD Charlottesville, Virginia Papanicolaou smears with atypical glandular cells of undetermined significance were correlated with significant findings in 45% of patients (32% with preinvasive or invasive lesions and 13% with benign lesions); prompt and aggressive workup is recommended.

------------------------------------------------------------------------ CLINICAL OPINION ------------------------------------------------------------------------

------------------------------------------------------------------------ Death of the Papanicolaou smear? A tale of three reasons Richard C. Boronow, MD Jackson, Mississippi The Papanicolaou smear, arguably the most cost-effective cancer screening test ever developed, is under siege, receiving intense legal, media, and even public and commercial challenge.

Understanding miscarriage or insensitive abortion: Time for more defined terminology? David J. R. Hutchon, MB Darlington, United Kingdom The term abortion for early pregnancy loss can cause offense; the word miscarriage in place of abortion is recommended for all English language journals.

------------------------------------------------------------------------ GENERAL OBSTETRICS AND GYNECOLOGY ------------------------------------------------------------------------

------------------------------------------------------------------------ Gynecology

Can the number of cigarettes smoked predict high-grade cervical intraepithelial neoplasia among women with mildly abnormal cervical smears? Sean Francis Daly, MD, Magella Doyle, MB, James English, MD, Michael Turner, MD, James Clinch, MD, Walter Prendiville, MD Dublin, Ireland This study demonstrates a dose-dependent association between the number of cigarettes smoked and the risk of cervical intraepithelial neoplasia grade 2 or 3.

Risk factors for familial and sporadic ovarian cancer among French Canadians: A case-control study Beatrice Godard, PhD, William D. Foulkes, MB, PhD, Diane Provencher, MD, Jean-Sebastien Brunet, MSc, Patricia N. Tonin, PhD, Anne-Marie Mes-Masson, PhD, Steven A. Narod, MD, Parviz Ghadirian, PhD Montreal, Quebec, and Toronto, Ontario, Canada Both familial and sporadic ovarian cancer share the same risk factors in a French Canadian population.

The cost-effectiveness of treating women with a cervical vaginal smear diagnosis of atypical squamous cells of undetermined significance Stephen S. Raab, MD, Ann L. Steiner, MD, John Hornberger, MD, MS Iowa City, Iowa, and Stanford, California For a woman with a diagnosis of atypical squamous cells of undetermined significance, simply repeating the smear is the most cost-effective follow-up strategy.

Qualification of atypical squamous cells of undetermined significance in an independent laboratory: Is it useful or significant? Mary F. Lachman, MD, Christina Cavallo-Calvanese, BS Stratford, Connecticut This study from a high-volume independent laboratory supports the usefulness of atypical squamous cells of undetermined significance as a diagnostic category for cervicovaginal cytologic diagnosis and subsequent patient management.

Elevated high-density lipoprotein cholesterol and dietary fat intake in women with cyclic mastopathy Pamela J. Goodwin, MD, MSc, Andrea Miller, BSc, MSc, MD, M. Elisabeth Del Giudice, BSc, MSc, William Singer, MD, Philip Connelly, MD, J.W. Knox Ritchie, MD Toronto, Ontario, Canada Elevations in high-density lipoprotein cholesterol and dietary fat intake are associated with severe cyclic mastopathy, suggesting that nutritional factors contribute to the pathophysiologic characteristics of this syndrome.

The effect of monocyte chemotactic protein 1 in intraperitoneal adhesion formation in a mouse model Hulusi B. Zeyneloglu, MD, Emre Seli, MD, Levent M. Senturk, MD, Linda S. Gutierrez, MD, David L. Olive, MD, Aydin Arici, MD New Haven, Connecticut Monocyte chemotactic protein 1 is expressed in a time-dependent manner in intraperitoneal adhesions in mice, and anti-monocyte chemotactic protein 1 neutralizing antibody decreases intraperitoneal adhesion formation.

Calcium carbonate and the premenstrual syndrome: Effects on premenstrual and menstrual symptoms Susan Thys-Jacobs, MD, Paul Starkey, MD, Debra Bernstein, PhD, Jason Tian, PhD, the Premenstrual Syndrome Study Group New York, New York, and Parsippany, New Jersey Calcium supplementation is an effective treatment in premenstrual syndrome, resulting in a major reduction in overall luteal phase symptoms.

------------------------------------------------------------------------ Obstetrics ------------------------------------------------------------------------

------------------------------------------------------------------------ Antepartum cervical ripening: Applying prostaglandin E2 gel in conjunction with scheduled nonstress tests in postdate pregnancies Jean M. Lien, MD, Mark A. Morgan, MD, Thomas J. Garite, MD, Kathleen A. Kennedy, MD, Deborah A. Sassoon, MD, Roger K. Freeman, MD Long Beach, Orange, and Anaheim, California, and Portland, Oregon Cervical ripening with prostaglandin E2 gel in conjunction with scheduled antepartum testing for postdate pregnancies may be efficacious only for selected patients.

Methadone maintenance in pregnancy: A reappraisal Haywood L. Brown, MD, Kathy A. Britton, RN, Danielle Mahaffey, MD, Edward Brizendine, MS, A. Kinney Hiett, MD, Mureena A. Turnquest, MD Indianapolis, Indiana Women receiving methadone maintenance are at high risk for illicit drug use and neonatal complications, including drug withdrawal.

Circulating vascular cell adhesion molecule-1 in pre-eclampsia, gestational hypertension, and normal pregnancy: Evidence of selective dysregulation of vascular cell adhesion molecule-1 homeostasis in pre-eclampsia John R. Higgins, MD, Aikaterina Papayianni, MD, Hugh R. Brady, MD, Michael R. N. Darling, MD, Joseph J. Walshe, MD Dublin, Ireland, and Boston, Massachusetts Induction of vascular cell adhesion molecule-1 expression in pre-eclampsia may contribute to leukocyte-mediated tissue injury or may reflect perturbation of previously unrecognized functions of this molecule in pregnancy.

Ethanol-induced expression of cytokines in a first-trimester trophoblast cell line David M. Svinarich, PhD, John A. DiCerbo, BA, Fadi M. Zaher, MS, Frank D. Yelian, MD, PhD, Bernard Gonik, MD Detroit, Michigan Expression of cytokines by first-trimester trophoblasts after ethanol exposure may provide a mechanism for altered fetal immune development in children with fetal alcohol syndrome.

Shoulder dystocia and associated risk factors with macrosomic infants born in California Thomas S. Nesbitt, MD, MPH, William M. Gilbert, MD, Beate Herrchen, PhD Davis and Berkeley, California Birth weight, assisted delivery, and diabetes were found to be independent and additive risk factors in 6238 cases (3% of births) of shoulder dystocia in infants weighing >3500 g.

In pregnancies with gestational diabetes mellitus and intensive therapy, perinatal outcome is worse in small-for-gestational-age newborns Apolonia Garcia-Patterson, MD, Rosa Corcoy, PhD, Montserrat Balsells, MD, Orenci Altirriba, PhD, Juan M. Adelantado, PhD, Lluis Cabero, PhD, Alberto de Leiva, PhD Barcelona, Spain Among women with gestational diabetes mellitus receiving intensive therapy, perinatal outcome is worse for small-for-gestational-age neonates than for appropriate- or large-for-gestational-age neonates.

The acute pressure natriuresis response blunted and the blood pressure response reset in the normal pregnant rat Shyama Masilamani, PhD, Gerald R. Hobbs, PhD, Chris Baylis, PhD Morgantown, West Virginia A blunted acute pressure natriuresis relationship and peripheral vasodilation are seen in late-pregnant rats, which permit cumulative sodium retention and plasma volume expansion without a rise in blood pressure.

Parathyroid hormone-related peptide (1 to 34) inhibits in vitro oxytocin-stimulated activity of pregnant baboon myometrium A. E. Pitera, G.C. S. Smith, MD, R. A. Wentworth, PhD, P. W. Nathanielsz, MD, PhD, ScD Ithaca, New York Nanomolar concentrations of parathyroid hormone-related protein inhibited in vitro oxytocin-stimulated activity in myometrium obtained before labor from all regions of the baboon uterus in the last third of pregnancy.

Uterine relaxation responses to calcitonin gene-related peptide and calcitonin gene-related peptide receptors decreased during labor in rats Yuan-Lin Dong, MD, PhD, Pandu R. R. Gangula, PhD, Li Fang, MD, Sinil J. Wimalawansa, MD, PhD, Chandrasekhar Yallampalli, DVM, PhD Galveston, Texas Uterine relaxation responses to calcitonin gene-related peptide and its receptors in the rat uterus are decreased during labor.

------------------------------------------------------------------------ Fetus-Placenta-Newborn ------------------------------------------------------------------------

------------------------------------------------------------------------ Potentially asphyxiating conditions and spastic cerebral palsy in infants of normal birth weight Karin B. Nelson, MD, Judith K. Grether, PhD Bethesda, Maryland, and Emeryville, California Potentially asphyxiating conditions, chiefly tight nuchal cord, were associated with an appreciable proportion of otherwise unexplained spastic quadriplegia but not with diplegia or hemiplegia.

An alternative for women initially declining genetic amniocentesis: Individual Down syndrome odds on the basis of maternal age and multiple ultrasonographic markers Ray Bahado-Singh, MD, Ozgur Deren, MD, Utku Oz, MD, Ann Tan, MD, David Hunter, MD, Joshua Copel, MD, Maurice J. Mahoney, MD, JD New Haven, Connecticut By combining maternal age and multiple ultrasonographic parameters, a high Down syndrome screening efficiency was obtained.

Hemostasis in the uteroplacental and peripheral circulations in normotensive and pre-eclamptic pregnancies John R. Higgins, MD, Joseph J. Walshe, MD, Michael R. N. Darling, MD, Lucy Norris, PhD, John Bonnar, MD Dublin, Ireland Preeclampsia is associated with an abnormal pattern of hemostasis in the uteroplacental circulation.

Prevention of herpes simplex virus infection and latency by prophylactictreatment with acyclovir in a weanling mouse model Anthony T. Dobson, MD, PhD, Bertis B. Little, PhD, L. Laurie Scott, MD Dallas, Texas Prophylactic acyclovir prevented acute and reduced the establishment of latent herpes simplex virus infection in a weanling mouse model.

Urocortin in pregnancy B. P. Glynn, PhD, A. Wolton, B. RodrĄguez-Li¤ares, PhD, S. Phaneuf, PhD, E. A. Linton, PhD Oxford, United Kingdom Urocortin was not translated to any great extent in pregnancy tissues investigated, nor was it detected in the circulation of pregnant women.

Doppler flow velocity waveforms of the umbilical arteries correlate with intravillous blood volume Thomas P. Hitschold, MD, PhD Wiesbaden, Germany Umbilical artery blood flow velocity waveforms depend on the volume of the fetoplacental vessel tree.

------------------------------------------------------------------------ AJOG REVIEWS ------------------------------------------------------------------------

------------------------------------------------------------------------ Cervical screening adjuncts: Recent advances Mark Spitzer, MD Jamaica, New York Recent advances in the technology used in cervical cancer screening have the potential to significantly increase the detection of cervical cancer and its precursors.

------------------------------------------------------------------------ LETTERS TO THE EDITORS ------------------------------------------------------------------------

------------------------------------------------------------------------ Recurrent candidiasis and "malcarbohydrate metabolism" Howard L. Smith, MD Roswell, New Mexico

Reply Jack D. Sobel, MD Detroit, Michigan

Fetal body composition and ultrasonographic estimates of fetal weight Ira Bernstein, MD, Patrick M. Catalano, MD Burlington, Vermont, and Cleveland, Ohio

Risk of magnesium for respiratory failure in pregnancy Michael P. Carson, MD, Rshmi Khurana, MD New Brunswick, New Jersey, and Providence, Rhode Island

Nonobstetric emergencies in pregnancy Russel D. Jelsema, MD Grand Rapids, Michigan

Databases and the statistical usage of (perinatal) results-Reply Roel Nijland, MD, PhD, Paul P. van den Berg, MD, PhD, Henk W. Jongsma, PhD Nijmegen, The Netherlands

Reply Johannes Egberts, PhD Leiden, The Netherlands

Some concerns about the new research guidelines for interpretation of electronic fetal heart rate monitoring Joao Bernardes, MD, PhD, Altamiro Costa Pereira, MD, PhD Porto, Portugal

Reply Julian T. Parer, MD, PhD San Francisco, California

Erb's palsy without shoulder dystocia William N. Spellacy, MD Tampa, Florida

Reply Robert Gherman, MD Portsmouth, Virginia

Clinical outcome of mild fetal ventriculomegaly Steven L. Bloom, MD, Deborah D. Bloom, PhD Dallas, Texas

Reply Patrizia Vergani, MD, Anna Locatelli, MD, Alessandro Ghidini, MD Monza, Italy, and Washington, D.C.

Are there seasonal effects on obstetric circadian rhythms? Michael Cooperstock, MD, MPH Columbia, Missouri

Reply Angelo Cagnacci, MD, Annibale Volpe, MD Modena, Italy

Maternal weight, body mass index, and cesarean delivery Barbara Luke, ScD, MPH, RD Ann Arbor, Michigan

Cesarean section Lee Ann Roberts, MD Raleigh, North Carolina

Reply Brian C. Brost, MD, Roger B. Newman, MD Keesler AFB, Mississippi

------------------------------------------------------------------------ READER SERVICE ------------------------------------------------------------------------

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