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Re: Precocious puberty From: Mark Perloe, M.D. (mperloe@ivf.com) Sat Aug 29 15:50:45 1998 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: José Luis Gómez-Palomares: "Magnesic Sulfat" Previous message: jay kulkin: "Re: Early pregnancy with adnexal mass" In reply to: DoctorJoe@aol.com: "Re: Precocious puberty" For precocious puberty you must use 10mg/month dose to see benefits. At 12:50 PM 8/29/98 -0500, you wrote: > >In a message dated 8/29/98 10:35:59 AM, you wrote: > ><<I am treating a 9-year old with monthly Zoladex (goserelin, 3.6mg). It >has stopped menstruation and she is growing (currently 146cms), but >breast development is continuing. This is a constitutional precocious >puberty, with no cause found after extensive investigation. She remains >a little girl emotionally, and the breast development is distressing >her. I guess its related to persisting low levels of E2 (we know from >treatment of Turners that you need low estrogens to promote breast >development), but I would welcome any advice.>> > >If her hypothalamus is sufficiency inhibited, where is the estrogen coming >from? Is she "fat" for her age? Is it peripheral conversion? Or does she have >a tumor you missed? > >Otherwise, does she need more drug? > >Joe P. > -- Mark Perloe, M.D. 285 Boulevard NE, Suite 320, Atlanta, GA 30312 404-265-3662 Visit our chatroom at http://www.ivf.com/chat.html Mon 8:00-9:30pm ET Next message: José Luis Gómez-Palomares: "Magnesic Sulfat" Previous message: jay kulkin: "Re: Early pregnancy with adnexal mass" In reply to: DoctorJoe@aol.com: "Re: Precocious puberty"

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