Precocious puberty

From: Cyril J van Gelderen (vangel@pixie.co.za)
Sat Aug 29 10:32:04 1998


I am treating a 9-year old with monthly Zoladex (goserelin, 3.6mg). It has stopped menstruation and she is growing (currently 146cms), but breast development is continuing. This is a constitutional precocious puberty, with no cause found after extensive investigation. She remains a little girl emotionally, and the breast development is distressing her. I guess its related to persisting low levels of E2 (we know from treatment of Turners that you need low estrogens to promote breast development), but I would welcome any advice. Ciaou CvG

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CvG




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