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Re: OB: Progesterone supportFrom: Bernard Cristalli (bcrist@club-internet.fr)Thu Aug 27 14:04:09 1998
Garry E. Siegel, M.D. wrote: > > I have just seen two infertility patients from differnt, reputable > clinics, who are on Progesterone Gel, Crinone, for support in the first > trimester. I am not familiar with using it, but both patients told me > that their docs told them that following the progesterone level was not > appropriate, since it acts locally, rather than systemically. > > Can any of the repro endo guys shed some light? > -- I'm not an ART guy but I worked on that subject. It is supposed to be a "first uterine pass effect" when progesterone is applied vaginally. It is pretty well documented about Utrogestan tablets (Besins*).
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