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Re: lupus and d.u.b. From: art fougner, md (evsono@pipeline.com) Fri Aug 21 07:56:50 1998 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: DoctorJoe@aol.com: "Re: C/S for condyloma" Previous message: Gail Waldby, MD: "Re: GYN: Endometriosis and TENS" In reply to: Kathi Wilson, BHSc, RM: "Re: Urine test strips" Next in thread: Braun, R. Daniel: "Re: Urine test strips" Howard: try this one - Endometrial carcinoma following chronic anovulation in a premenopausal woman with systemic lupus erythematosus. Sekiya S, Iwasaki H, Takeda B, Takamizawa H Department of Obstetrics and Gynecology, Chiba University School of Medicine, Japan. Endometrial carcinoma was diagnosed in a premenopausal woman suffering with systemic lupus erythematosus. She had received both prednisolone and an immunosuppressive agent for more than 10 years. Anovulatory cycles persisted during drug administration, along with dysfunctional uterine bleeding. The serum estrogen: progesterone ratio was high. Repeated endometrial biopsies revealed a progression of change from benign proliferation to cystic hyperplasia, adenomatous hyperplasia, atypical hyperplasia and invasive adenocarcinoma. These clinical data suggest that a result of long-term unopposed endogenous estrogen can have been the cause of the endometrial carcinoma. good luck! Art At Thu, 20 Aug 1998, HOWARD G. GELFAND, M.D. wrote: > >Does anyone know of any articles published that show a definitive link between S.L.E. and abnormal uterine bleeding? I know there is a relationship due to the thrombolic phenomenon that occurs with the Lupus antibody and have seen several patients over the years who have by history very heavy periods and lupus without any other cause. Thanks for any help. I have an insurance company claims analyst (not a physician) refusing to give coverage for this woman's care because he can't find any information in"Harrison's Principle of Internal Medicine" and so is refusing to cover any care rendered until she meets a $2000.00 deductible!! Help. >Howard G. Gelfand, M.D. >private practice -N.Y. (I must be crazy!!) -- art fougner, md SonoScan/Genetic Sciences forest hills, ny evsono@pipeline.com Next message: DoctorJoe@aol.com: "Re: C/S for condyloma" Previous message: Gail Waldby, MD: "Re: GYN: Endometriosis and TENS" In reply to: Kathi Wilson, BHSc, RM: "Re: Urine test strips" Next in thread: Braun, R. Daniel: "Re: Urine test strips"

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