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Re: Compounded prostaglandin gel for cervical ripeningFrom: Luis Sanchez-Ramos (sanchez-ramos@worldnet.att.net)Sun May 31 11:30:16 1998
At Sat, 30 May 1998, Douglas Krell MD wrote: >When will this data be available? The data are already available: The intravaginal use of misoprostol tablets have been compared with Prepidil (0.5 mg of intracervical dinoprostone PGE2 gel) in at least 7 randomized clincial trials. All have shown misoprostol to be as effective or more effective than Prepidil. A partial list of references can be obtained from our meta-analysis published in Obstet Gynecol 1997;89:633-42. We and others have also compared the safety and efficacy of misoprostol with Cervidil (10 mg controlled release dinoprostone[PGE2]). In our study, Obstet Gynecol 1998;91:401-5., we concluded that misoprostol was more effective and less expensive than Cervidil. Another study from California reached similar conclusions Am J Obstet Gynecol 1997;177:612-8.
-- Luis Sanchez-Ramos, MD
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