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Re: Depo Provera for endometrial hyperplasia From: J. Hellriegel (jhellrie@pce.net) Wed May 27 18:41:14 1998 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Jae-Sook Roh: "Help me" Previous message: Paul Prior MD: "Depo Provera for endometrial hyperplasia" In reply to: Paul Prior MD: "Depo Provera for endometrial hyperplasia" At Wed, 27 May 1998, Paul Prior MD wrote: > >Anyone have a reference for treating endometrial hyperplasia (simple >no atypia) with DMPA (depo provera)? > -- Unique Identifier 90314331 Authors Lindahl B. Alm P. Ferno M. Norgren A. Institution Department of Obstetrics and Gynecology, Oncology University Hospital, Lund, Sweden. Title Endometrial hyperplasia: a prospective randomized study of histopathology, tissue steroid receptors and plasma steroids after abrasio, with or without high dose gestagen treatment. Source Anticancer Research. 10(3):725-30, 1990 May-Jun. Abstract 274 patients with spontaneous endometrial hyperplasias were randomized into two groups: one treated with only abrasio, and another with additional 500 mg medroxyprogesterone acetate (MPA) twice weekly for 3 months. Total disappearance of all types of hyperplasias was seen following MPA treatment, whereas with only abrasio about 60% were removed suggesting that MPA does not have to be generally given to eliminate endometrial hyperplasias. Quantitative determinations of tissue steroid receptors and plasma steroids do not seem to be useful for the selection of patients in need of gestagen treatment. Registry Numbers 0 (Antineoplastic Agents). 0 (Delayed-Action Preparations). 0 (Receptors, Estrogen). 0 (Receptors, Progesterone). 50-28-2 (Estradiol). 520-85-4 (Medroxyprogesterone). 57-83-0 (Progesterone). 63-05-8 (Androstenedione). 71-58-9 (Medroxyprogesterone 17-Acetate). -- J. Hellriegel, Jr., MD, PhD Next message: Jae-Sook Roh: "Help me" Previous message: Paul Prior MD: "Depo Provera for endometrial hyperplasia" In reply to: Paul Prior MD: "Depo Provera for endometrial hyperplasia"

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