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Re: Cystic fibrosis From: Malcolm Griffiths (Malcolm@MGRIFF22.demon.co.uk) Sun May 17 15:32:35 1998 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Richard M. Roberts: "Re: Cystic fibrosis" Previous message: Bernard Cristalli: "Re: Vaginal Intercourse..." Maybe in reply to: Tim and Jude Kurokawa: "Cystic fibrosis" Next in thread: Richard M. Roberts: "Re: Cystic fibrosis" Reply: Richard M. Roberts: "Re: Cystic fibrosis" In message <0074a5920041058FM02@mail.fm>, Lisa Boisvert-Mackenzie <libo@mail.fm> writes > >Jude, >One of the questions I ask when clients consider testing for genetic >abnormalities is "what do you want to do with this information?" Some >clients want the option of termination, others will continue the pregnancy >regardless, so I ask do you want to worry throughout the pregnancy for a >test that is accurate such and such percent of the time or do you wish to >pursue further testing that entails so-and-so and predicts with such and >such accuracy. Some think about it and decide they will accept this baby >however it is, others need to know more before they can decide and/or >prepare and will opt for more testing and some will terminate if the baby >does not seem "perfect." Agree largely with above. > >Anne Frye suggests a radioimmunoassay for serum trypsin. She also states >"About 5 % of the Caucasian population carries the gene and 1 in 2000 >infants will be affected." This is from 'Undersanding Diagnostic Tests in >the Childbearing Year.' Not familar with this text (or date of text), but I think it is pretty well out of date since confirmation of the site of the CF gene and ability to assay for deletion defects at that site. -- Malcolm Griffiths MD,MRCOG,MFFP,Cert.Mgmnt Obstetrician & Gynaecologist Luton & Dunstable Hosp.,UK. Tel: 01582-497459 (office) Fax: 01582-497376 01525-222849 (home) email: Malcolm@mgriff22.demon.co.uk http://www.obgyn.net/board/griffith.htm "CLINICAL FREEDOM IS THE LAST REFUGE OF THE CLINICALLY INCOMPETENT!" (Someone [1997]) Next message: Richard M. Roberts: "Re: Cystic fibrosis" Previous message: Bernard Cristalli: "Re: Vaginal Intercourse..." Maybe in reply to: Tim and Jude Kurokawa: "Cystic fibrosis" Next in thread: Richard M. Roberts: "Re: Cystic fibrosis" Reply: Richard M. Roberts: "Re: Cystic fibrosis"

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