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Re: Steriod Therapy for HyperemesisFrom: art fougner, md (evsono@pipeline.com)Tue May 12 07:53:41 1998
here's the reference! hope this helps. art Successful management of hyperemesis gravidarum using steroid therapy. QJM 1996 Feb;89(2):103-7 Taylor R [Find other articles with this Author] Department of Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, UK. Hyperemesis gravidarum causes uncontrollable vomiting, severe dehydration and muscle wasting in pregnancy and usually requires weeks or months of intravenous fluid therapy. A consecutive series of 7 women with hyperemesis gravidarum were treated with high-dose steroid therapy. Vomiting stopped within 3 h of the first dose of intravenous hydrocortisone in all patients. Maintainence oral prednisolone therapy in doses up to 45 mg/day permitted discharge from hospital within days, resumption of normal eating, reversal of muscle wasting and regain of lost weight (mean loss from prepregnant weight 10.5 +/- 4.3 kg). Prednisolone in doses of 15 mg/day or more was required for 10.6 +/- 4.7 (range 6-20) weeks. High-dose prednisolone therapy is effective in suppressing symptoms of intractable hyperemesis gravidarum and allowing normal maternal nutrition.
At Mon, 11 May 1998, wrote:
>
-- art fougner, md SonoScan/Genetic Sciences forest hills, ny evsono@pipeline.com
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