Re: Misoprostol *induction* versus ripening

From: Anna Meenan, MD (annam@uic.edu)
Sat Apr 18 12:48:06 1998


At Thu, 16 Apr 1998, Tim and Jude Kurokawa wrote: >
>When you find that partially disolved tab, rub it around the posterior
>fornix and wait another couple of hours. You might just be surprised. I
>sure was. Couple times she blooms into fulblown labor.
>If nothing, then another 50 mcg. All you're loosing is a couple of hours.
>
>Jude
>V<>V<>V<>V<>V<>V<>V<>V
>Jude Kurokawa, CNM, FNP
>513 Dayton St. Wolf Point, MT 59201 406-653-1608
>Home and Hospital births on the Rez
>The Coyote midwife sits by the hole and waits....
>mailto:jkuro@midrivers.com HTTP://www.midrivers.com/~jkuro
>V<>V<>V<>V<>V<>V<>V<>V<>V
>
>-----Original Message-----
>From: Garry E. Siegel, M.D. <garrys@mindspring.com>
>To: Multiple recipients of list <ob-gyn-l@talk.obgyn.net>
>Date: Thursday, April 16, 1998 7:41 PM
>Subject: OB: Misoprostol *induction* versus ripening
>
>>My hospital just has started a protocol, and it is essentially written
>>for ripening--50 mcg. intravaginally every four hours, unless
>>contracting every 7 minutes.
>>
>>Anyway, today after the second dose, the patient had changed her cervix
>>from 0/0 to 0/70%, and was contracting every 4 minutes, regularly, but
>>mild (she barely felt them).
>>
>>I wanted to keep going, but the nurses were reluctant. What do ya'll
>>do? Does anyone keep going with this for induction, and when do you stop
>>re-inserting. Also, the misoprostol tablets (100 mcg., cut in half)
>>were not fully dissolved when I went to reinsert at 4 hours, as I got a
>>partially dissolved tablet in return.
>>
>>Garry
>>
>>Please reply to the list or email privately
>>'
>>
>>--
>>Garry E. Siegel, M.D., FACOG
>>Private Practice
>>Roswell, Ga.

The nurses at our hospital tell (admittedly anecdotal) stories of these inductions frequently resulting in rapid precipitous labors that "blast the baby out of there" in just a few hours, not unlike the old days of buccal pitocin. Since it's not FDA approved for that purpose, I'd be cautious about pushing it.

--
Anna Meenan, MD




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