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Re: Oral cytotec From: Douglas Krell MD (dougkrell@roadrunner.com) Mon Apr 6 08:35:03 1998 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: art fougner, md: "GEN: Get Ready For the Phone Calls" Previous message: james Connerth md: "Recent acquisition of Greg Gapp md facog" Maybe in reply to: Douglas Krell MD: "Oral cytotec" Next in thread: nalbf@ime.net: "Re: Oral cytotec" -----Original Message----- From: Luis Sanchez-Ramos <sanchez-ramos@worldnet.att.net> To: Multiple recipients of list <ob-gyn-l@talk.obgyn.net> Date: Monday, April 06, 1998 7:06 AM Subject: Re: Oral cytotec >At Mon, 6 Apr 1998, Douglas Krell MD wrote: > How often have you gone to >>redose a cytotec patient and found the pill yet unabsorbed from the vagina? >>Too often in my experience. >>Also dosing is more convenient and it can be administered by the nursing >>staff. In our hospital, the physician must give the medication. > >Clinical trials have shown that the oral adfministration of misoprostol >is associated with a higher incidence of increased uterine activity and >hyperstimulation syndrome. references? Higher doses are required when given orally. the absolute amount shouldn't matter as much as the variations in absorption, reliability, and safety for any given route of administration. >Why can a nurse administer this drug orally but a physician MUST insert >it vaginally ? You know how stubborn L and D nurses can be. >Occasionally an intact tablet will be found in patients requiring a >second dose of misoprostol. According to Dr. Krell, too often in his >experience. How often has intravaginally-administered misoprostol >failed ? Very rartely in my experience. So THIS is why the literature can be helpful. Doug. Next message: art fougner, md: "GEN: Get Ready For the Phone Calls" Previous message: james Connerth md: "Recent acquisition of Greg Gapp md facog" Maybe in reply to: Douglas Krell MD: "Oral cytotec" Next in thread: nalbf@ime.net: "Re: Oral cytotec"

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