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Re: OB: Downs Screning From: art fougner, md (evsono@pipeline.com) Fri Apr 3 07:21:52 1998 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: ATB28: "Re: OB: Downs Screning" Previous message: art fougner, md: "Re: OB: Downs Screning" In reply to: Peter Wein: "Re: OB: Downs Screning" Next in thread: ATB28: "Re: OB: Downs Screning" agreed. providing that the scan is performed by someone who has experience looking at fetuses. art At Fri, 03 Apr 1998, Peter Wein wrote: > >At 10:30 PM 02/04/98 -0600, you wrote: >>In a message dated 98-04-02 12:03:08 EST, gklein@bcm.tmc.edu writes: >> >><< Maternal blood tests taken during the first trimester of pregnancy can >>detect the majority of fetuses affected with Down's syndrome, >> >> >>This is old news for those who have kept up with events abroad, where >>screening for fetal chromosome abnormalities, including Down syndrome, using >>both biochemical and ultrasound has been available for some time now. >> >>The major problem as I see it, is the lack of a reliable first trimester >>biochemical screening test for fetal neural tube defects. Neither hCG nor >>PAPP-A facilitates detection of NTDs. Thus, second trimester screening is >>still necessary. How many patients, docs, and plans will reliably succeed >in a >>2-step model? It'll be interesting to follow the literature and clinical >>experience on this one! >> >>Allan T. Bombard, MD >> >Even with first-trimester combined u/s and biochemical screening for >anueploidy, there will still be a necessity for 18 or so week scanning for >morphology, which is far superior to biochemical testing in terms of NTD >detection - and in any case 12 week scan will detect the anencephalics. > >-- >Peter Wein >Senior Lecturer >Department of Obstetrics and Gynaecology >University of Melbourne, Mercy Hospital for Women >Clarendon Street, East Melbourne 3002 >Australia >Tel: +61 3 9270 2556 Fax: +61 3 9417 5406 Mobile: 0414 691690 > -- art fougner, md SonoScan/Genetic Sciences forest hills, ny evsono@pipeline.com Next message: ATB28: "Re: OB: Downs Screning" Previous message: art fougner, md: "Re: OB: Downs Screning" In reply to: Peter Wein: "Re: OB: Downs Screning" Next in thread: ATB28: "Re: OB: Downs Screning"

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