Re: OB: Downs Screning

From: art fougner, md (evsono@pipeline.com)
Fri Apr 3 07:19:57 1998


allan,

a midtrimester scan with attention paid to the cerbellum and the shape of the calvarium seems more than sufficient to supplant afp as far as NTD is concerned.

art

At Thu, 2 Apr 1998, ATB28 wrote: >
>In a message dated 98-04-02 12:03:08 EST, gklein@bcm.tmc.edu writes:
>
><< Maternal blood tests taken during the first trimester of pregnancy can
>detect the majority of fetuses affected with Down's syndrome, >>
>
>This is old news for those who have kept up with events abroad, where
>screening for fetal chromosome abnormalities, including Down syndrome, using
>both biochemical and ultrasound has been available for some time now.
>
>The major problem as I see it, is the lack of a reliable first trimester
>biochemical screening test for fetal neural tube defects. Neither hCG nor
>PAPP-A facilitates detection of NTDs. Thus, second trimester screening is
>still necessary. How many patients, docs, and plans will reliably succeed in a
>2-step model? It'll be interesting to follow the literature and clinical
>experience on this one!
>
>Allan T. Bombard, MD

--
art fougner, md
SonoScan/Genetic Sciences
forest hills, ny
evsono@pipeline.com




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