Re: GYN/INFERTILITY: Crinone

From: Bernard Cristalli (bcrist@club-internet.fr)
Mon Mar 30 14:56:03 1998


Kelly Shanahan, MD wrote: >
> Oh wise REs of the list:
> While I realize that Crinone provides good
> endometrial levels without high serum levels, I would like your
> experience with Crinone (this is the first patient I've had on it). She
> has had 2 SABs in the past, knows about progesterone levels and is
> worried, despite my explanation of how Crinone works. From the
> convenience standpoint, she likes it and money is not an issue.
>
> Have you used Crinone before?
>
> What's your experience with it?
>
> Do you think it's as effective as a) vaginal suppositories or b) IM
> injections?
>
--
I worked on those vaginal shapes.
Crinone is supposed to be as effective as vaginal suppositories, and
more than IM shots. As you said: low serum levels and high endometrial
levels. This has been called first uterine pass effect, probably due to
local vascular reasons.
--
Bernard Cristalli MD CNGOF
AIHP - ACCA
Paris - France
http://www.obgyn.net/corresp/cristalli.htm




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