Re: Menopause and HRT

From: Bernard Cristalli (bcrist@club-internet.fr)
Thu Mar 19 23:31:17 1998


Caryn Rybs wrote: >
> Case report:
> 47 years old female, healthy and athletic.
> T.A.H. at 41 for fibroid tumors.
> Pulmonary embolism in the past (post-partum )
> Protein C deficiency runs in the family.
> Refuses anticoagulation therapy.
> 4 sisters with history of pulmonary embolism.
> All four of them are under long term warfarin therapy
> Mother, 67 years old with severe osteoporosis.
>
> Any suggestion on how to approach HRT for that patient ?
>
> Has she been checked for protein C deficiency? If she is not deficient and wants to try HRT,
> I would offer her that but would have her sign informed consent stating she understands
> risk of DVT/PE and the possibility of significant morbidity and mortality.
>
--

OK. and if she is Prot C deficient: no HRT

--
Bernard Cristalli MD CNGOF
AIHP - ACCA
Paris - France
http://www.obgyn.net/corresp/cristalli.htm




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