Re: Zofran and Hyperemesis

From: Dean Huffman (perinatl@slip.net)
Wed Mar 18 22:48:29 1998


At 09:28 PM 3/17/98 -0600, you wrote: >In message <00a701bd4e05$f5facfa0$4d204486@rbraun.iupui.edu> writes:
>> Is it safer than Bendectin?? Which was taken off the market.
>
>It would be awfully hard for anything to be safer than Bendectin. It is
>probablyt the most-studied drug for use in pregnancy in the history of the
>world, with no evidence of harm.
>
>---------------------------------------------------------------------------
>
>---------------------------------------------------------------------------
>
>---------------------------------------------------------------------------
>Bob Woolley
>St. Paul, Minnesota
>
>"WITHOUT CENSORSHIP, THINGS CAN GET TERRIBLY CONFUSED IN THE PUBLIC MIND."
> -General William Westmoreland, during the war in Viet Nam
>

Dr. Brent from Jefferson medical school (I believe), a terratologist, talks about two kinds of chemicals as related to pregnancy. One is a terratogen, such as Thalidamide. The other kind of substance is a litogen, i.e., a substance that causes no problems such as birth defects, but does cause litigation. Bendictin falls in that second category. It is a litogen.

In fact, Bendectin made it all the way to the US Supreme Court about five or so years ago in a case titled:

DAUBERT et ux., individually and as guardians and litem for DAUBERT, et al.

v.

MERRELL DOW PHARMACEUTICALS, INC.

certiorari to the united states court of appeals for the ninth circuit

No. 92-102. Argued March 30, 1993 -- Decided June 28, 1993

This case can be viewed at: http://supct.law.cornell.edu/supct/html/92-102.ZS.html

--
==================================================================
Dean G. Huffman     Phone: 217 787-3745  FAX 217 787-0680 (Home)
perinatl@slip.net          217 782-9666      217 524-2432 (Office)

This is a court of law, young man, not a court of justice. -- Oliver Wendell Holmes, Jr. H ==================================================================





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