|
|
 |
 |
 |
|
|
|||
|
||||
|
||||
Re: Abnormal triple screeFrom: art fougner, md (evsono@pipeline.com)Wed Feb 25 11:01:47 1998
At Wed, 25 Feb 1998, Gary Kleinman wrote: > >I have a patient who is a 31 year old g3p0 @ 18 weeks. She is on syntrhoid, >pregnancy otherwise uncomplicated. No bleeding. Her tripple screen showed: > >AFP: 2.6 MoM >Estriol: 2.16 MoM >HcG: 7.33 MoM > >Utrasound shows no placental or fetal abnormalities. The lady is heavy and >the sonographers raised a question of cleft lip and palate which could no >be confirmed. The fingers look normal as does the head, heart and spine. > >Would you recommend amnio? Fetal assessment (NST's etc) later? Any special >studies? > >Thanks in advance, > >-- >Gary Kleinman > >Gary E. Kleinman, M.D. >Perinatologist/Geneticist >Perinatal Center >3196 S. Maryland Ave >Las Vegas, NV 89109 >702 732-9332 >702 732-4472 (Fax) > hi your patient most likely has an abnormal placenta. genetic counseling should be offered since there is about a 1% incidence of abnormal karyotype. additionally, this patient is at increased risk for adverse perinatal outcome and should be viewed as high risk. the following references may help - Prenat Diagn 1997 Nov;17(11):1039-1046 Maternal serum alpha-fetoprotein and human chorionic gonadotropin in pregnant women with acute parvovirus B19 infection with and without fetal complications. Komischke K, Searle K, Enders G Prenat Diagn 1997 Jul;17(7):601-606 The HELLP syndrome: its association with unexplained elevation of MSAFP and MShCG in the second trimester. Morssink LP, Heringa MP, Beekhuis JR, De Wolf BT, Mantingh A Prenat Diagn 1996 Dec;16(12):1129-1135 Maternal serum testing for alpha-fetoprotein and human chorionic gonadotropin in high-risk pregnancies. Jauniaux E, Gulbis B, Tunkel S, Ramsay B, Campbell S, Meuris S J Matern Fetal Med 1996 Nov;5(6):340-344 Maternal serum human chorionic gonadotropin as a marker for the delivery of low-birth-weight infants in women with unexplained elevations in maternal serum alpha-fetoprotein. Hurley TJ, Miller C, O'Brien TJ, Blacklaw M, Quirk JG Jr Fetal Diagn Ther 1996 Jul;11(4):249-253 Maternal serum triple analyte screening and adverse pregnancy outcome. Milunsky A, Nebiolo L Prenat Diagn 1996 May;16(5):431-435 The detection of non-immune hydrops through second-trimester maternal serum screening. Saller DN Jr, Canick JA, Oyer CE Br J Obstet Gynaecol 1996 Mar;103(3):209-213 Velamentous umbilical cord insertion may be suspected from maternal serum alpha-fetoprotein and hCG. Heinonen S, Ryynanen M, Kirkinen P, Saarikoski S Prenat Diagn 1995 Dec;15(12):1121-1124 Elevated alpha-fetoprotein and human chorionic gonadotropin as a marker for placental trisomy 16 in the second trimester? Zimmermann R, Lauper U, Streicher A, Huch R, Huch A Am J Obstet Gynecol 1994 Oct;171(4):1038-1041 Elevated second-trimester human chorionic gonadotropin levels in association with poor pregnancy outcome. Wenstrom KD, Owen J, Boots LR, DuBard MB good luck! art
-- art fougner, md SonoScan/Genetic Sciences forest hills, ny evsono@pipeline.com
|
|
Return to
|
Mail a New Message to the Forum: ob-gyn-l@obgyn.net Forum Administrator: geffrey.klein@obgyn.net Report Technical Problems: webmaster@obgyn.net Last Updated: Mon Nov 2 05:27:05 2009 |
The American Medical Association is no longer designating CME hours for AMA Category II CME credit. However, physicians themselves may self designate learning activities as Category II CME credit hours if they feel it is of sufficient educational merit and meets the formal definitions of continuing medical education. OBGYN.net believes these interaction in this forum meets these criteria. For further information see the AMA web site.