Re: Prematurity vs Chemotherapy

From: DoctorJoe (DoctorJoe@aol.com)
Tue Dec 30 09:09:23 1997


In a message dated 97-12-30 09:24:32 EST, you write:

<< Patient is pregnant 28.5 weeks gestation. B-CELL Lymphoma, occupying most of the left lung and mediastinum. On MRI there is no involvement of the spleen, liver or retroperitoneal lymph-nodes. Patient is considered for Cytoxan, Oncovin, Adriamycin and Prednison treatmen.

Should the fetus be delivered before chemotherapy ?

The dilemma: complications of prematurity versus unknown long term sequelae of chemotherapy exposure in utero.

Can anyone help ? >>

My recollection is that Prednisone and Cytoxan are "benign" in pregnancy. I'm not immediately familiar with Oncovin and Adria... I would seriously consider initiating chemo therapy and push for fetal maturity...

Joe P.





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