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Re: Tocolysis vs. Placebo (was Magnesium Sulfate increases perinatal mortality??) From: Bernard Cristalli (bcrist@club-internet.fr) Fri Dec 26 13:54:02 1997 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Bernard Cristalli: "Re: GEN: Re:Travel plans to Paris" Previous message: Robert J. Woolley: "Re: Health Insurance/HMO's" Maybe in reply to: Malcolm Griffiths: "Tocolysis vs. Placebo (was Magnesium Sulfate increases perinatal mortality??)" Next in thread: Peter Wein: "Re: Tocolysis vs. Placebo (was Magnesium Sulfate increases" Malcolm Griffiths wrote: > > In message <3.0.3.32.19971226142309.00804bb0@ariel.ucs.unimelb.EDU.AU>, > Peter Wein <p.wein@obstetrics_mercy.unimelb.EDU.AU> writes > >Malcolm, with respect this is rubbish - consult the Cochrane database, as I have > >posted before. Both beta-mimetics and indomethacin are effective in decreasing > >delivery within 48 hours,... > >. It is incorrect to say > >that there is no evidence that currently licensed tocolytics work better than > >placebo. ... > THIS BENEFIT IS TO ALLOW A PROPORTION OF > WOMEN AND THEIR BABIES TO BENEFIT FROM THE SMALL WINDOW TO ALLOW THE > STEROIDS TO WORK. There is no other demonstrated advantage of tocolysis > in TPL. > > 1) Indomethacin tocolysis in preterm labour: "there was no difference in the incidence of > fetal death, neonatal death, and respiratory distress syndrome" > and > "There are inadequate data from controlled evaluations to assess the > perinatal effects of indomethacin for the arrest of preterm labour" > > 2) Betamimetic tocolytics in preterm labour > "There is no evidence that they, of themselves, have a beneficial effect > on the fetus or the infant. > > My view is that no benefit will be seen unless steroids are given. Some > women in TPL will additional benefit from tocolysis ONLY IF STEROIDS ARE > ALSO GIVEN. > -- I Could not say more. -- Bernard Cristalli MD CNGOF AIHP - ACCA Paris - France http://www.obgyn.net/corresp/cristalli.htm Next message: Bernard Cristalli: "Re: GEN: Re:Travel plans to Paris" Previous message: Robert J. Woolley: "Re: Health Insurance/HMO's" Maybe in reply to: Malcolm Griffiths: "Tocolysis vs. Placebo (was Magnesium Sulfate increases perinatal mortality??)" Next in thread: Peter Wein: "Re: Tocolysis vs. Placebo (was Magnesium Sulfate increases"

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