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Re: Unidentified subject!From: Terry J. DuBose (tjdubose@juno.com)Sun Nov 30 18:01:30 1997
Bill, thanks for the input and support for the "trophotropism" theory of placental migration, etc. Now, you may have hit on something as far a using power Doppler to study the phenomenon. Harris and I talked about how to get "hard data" on this. He felt that the best way would be to document the cord insertion relative to the edges of the placenta, and then later reevaluate to determine if the cord insertion was closer to one edge. That seems a difficult study to undertake the population will have to be huge in order to come up with even a moderate number of placentas that fit the criteria. How would you approach such a study? I ask this because of you extensive understanding of perfusion and vascular Doppler. Also, since you have less experience with obstetrical work, you may come up with something that is just too obvious to those who do OB everyday. Any suggestions welcome. Peace, Terry J. DuBose On Sun, 30 Nov 1997 16:57:45 -0700 "William Johnson" <BJohnson@salud.unm.edu> writes: Bill Johnson, Albuquerque, NM Terry DuBose wrote of Harris Finburg's feeling that: >>> "...the placenta has a propensity to grow toward areas of richer uterine perfusion and to atrophy in areas of reduced perfusion." <<< << Regarding the subject of "trophotropism", Harris Fineburg's argument makes sense to this vascular-oriented bystander. Obviously this subject is out of my area, but I definitely believe there are numerous places where our knowledge of physiology is severely lacking. It often seems to me that, while we are concentrating on finding vessel obstruction with Doppler, we are overlooking perfusion issues. But the recent introduction of power Doppler provides another tool to evaluate organ perfusion noninvasively. I am not always sure of the usefulness of power Doppler, as it is subjective and not quantifiable, but I wonder if it would be applicable regarding the relationship of uterine perfusion to velamentous membrane development?
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