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Re: Tamoxifen and endometrial thicknessFrom: art fougner, md (evsono@pipeline.com)Fri Nov 14 08:47:06 1997
At Fri, 14 Nov 1997, Dr Naimish Patel wrote: > >Recently I have two postmenopausal patients on Tamoxifen who had routine >u/s scans which revealed endometrial thickness of >10mm. At >hysteroscopy both women had atrophic endometrium, in fact one had such >an atrophic cavity that I thought I had created a false passage.Does >Tamoxifen cause any known type of abnormality of the endometrium which >may masquerade as increased endometrial thickness or should I have a >word the U/S dept ?. > >-- >Dr Naimish Patel >Bunbury Hospital >Western Australia > YES! this has been reported by Steve Goldstein at NYU, among others. apparently what you see as a prominent endometrial stripe may actually represent subendometrial adenomyosis. in these cases, instillation of saline into the uterine cavity (sonohysterography) is suggested to further evaluate the true nature of Tamoixfen-induced changes. art
-- art fougner, md SonoScan/Genetic Sciences forest hills, ny evsono@pipeline.com
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