|
|
 |
 |
 |
|
|
|||
|
||||
|
||||
Re: Dapsone (was Brown Recluse Spider Bite)From: Arthurfree@aol.comWed Oct 1 21:55:09 1997
I haven't reviewed the rationale for a while, but the function of Dapsone in brown recluse bites has nothing to do with its anti-microbial activity. It has something to do with red cell stabilization and it is used in patients who seem to be getting a systemic syndrome (fever, hemolysis) associated with the bite. They rarely have significant infection, the erythema is largely due to toxins and the majority do very well. We have done lots of things in the past (wide excision comes to mind) due to the few horendous results that occur with extensive necrosis. Experts now recommend (code for "I've not seen the studies myself") the use of topical nitroglycerine early on. Apparently it causes increased blood flow to the area to mobilize and dilute the toxin reducing the amount of necrosis. I see four or five a year and I can't remember the last time I saw one that needed grafting/reconstruction though a lot of that has to do with location. Arthur Freeland Warrensburg Missouri
|
|
Return to
|
Mail a New Message to the Forum: ob-gyn-l@obgyn.net Forum Administrator: geffrey.klein@obgyn.net Report Technical Problems: webmaster@obgyn.net Last Updated: Mon Nov 2 05:24:50 2009 |
The American Medical Association is no longer designating CME hours for AMA Category II CME credit. However, physicians themselves may self designate learning activities as Category II CME credit hours if they feel it is of sufficient educational merit and meets the formal definitions of continuing medical education. OBGYN.net believes these interaction in this forum meets these criteria. For further information see the AMA web site.