Re: MSAFP vs triple screen

From: Cheri Van Hoover (cherivh@waonline.com)
Sun Jul 13 10:49:42 1997


Samir Saidi wrote: >
> Thanks, Danny, and other listers. I agree with the points.
>
> I think the point I was trying to iterate in my first post, rather than
> start a debate on FNT was to emphasise the attitude to Down's screening
> in the community, i.e. "Have a test for Down's". That's the way it
> appears to be presented to our antenatal patients, without any
> significant explanation of the implications and inadequacies of the
> test(s).
>
> Any comments?

I recently wrote an 8 page paper on the ethical implications of prenatal diagnosis. I agree that this is an area which has been sadly neglected in the rush to embrace new technologies. Informed consent for genetic screening is very difficult because of the complexity of the legal, ethical, and moral issues involved in this testing. Here's my reference list, for those who are interested in reading more. If anyone is interested in the paper itself, let me know and I'd be happy to send it to you.

--
Cheri Van Hoover, CNM
Midwifery Service at Stanford
Palo Alto, CA

Asch, D.A., Hershey, J.C., Pauly, M.V., Patton, J.P., Jedrziewski, M.K., & Mennuti, M.T. (1996, May). Genetic screening for reproductive planning: methodological and conceptual issues in policy analysis. American Journal of Public Health, 86(5), 684-690.

Council on Ethical and Judicial Affairs, American Medical Association (1994, July). Ethical issues related to prenatal genetic testing. Archives of Family Medicine, 3(7), 633-642.

de Montalembert, M., Guilloud-Bataille, M., Ducros, A., Galacteros, F., Girot, R., Herve, C., Maier-Redelsperger, M., & Feingold, J. (1996). Implications of prenatal diagnosis of sickle cell disease. Genetic Counseling, 7(1), 9-15.

Elkins, T.E., & Brown, D. (1995, Spring). Ethical concerns and future directions in maternal screening for Down syndrome. Women's Health Issues, 5(1), 15-20.

Ganiats, T.G. (1996, January-March). Justifying prenatal screening and genetic amniocentesis programs by cost-effective analyses: a re-evaluation. Medical Decision Making, 16(1), 45-50.

Glover, N.M., & Glover, S.J. (1996, August). Ethical and legal issues regarding selective abortion of fetuses with Down syndrome. Mental Retardation, 34(4), 207-214.

Khalid, L., Price, S.M., & Barrow, M. (1994, March). The attitudes of midwives to maternal serum screening for Down's syndrome. Public Health, 108(2), 131-136.

Murray, T.H. (1994, Fall). Assessing genetic technologies. Two ethical issues. International Journal of Technology Assessment in Health Care, 10(4), 573-582.

Searle, J. (1996, August). Fearing the worst--why do pregnant women feel 'at risk'? Aust. and N.Z. Journal of Obstetrics and Gynaecology, 36(3), 279-286.

Sheridan, E., Williams, J., Caine, A., Morgan, R., Mason, G., & Mueller, R.F. (1997, January). Counselling implications of chromosomal abnormalities other than trisomy 21 detected through a maternal serum screening programme. British Journal of Obstetrics and Gynaecology, 104(1), 42-45.





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