Re: Misoprostol oral vs Vaginal

From: Clifford J. Goodman, Jr., MD (momdoc@getnet.com)
Sat Jul 5 11:12:43 1997


James E. Sumners wrote:

> At Mon, 30 Jun 1997, Geffrey H. Klein, MD wrote:
> The other article in the Green: I thought it would be interesting for
> the list because there has been so much talk about misoprostol:
>
> So I guess it looks like we will ultimately be using it vaginally?
>
> Actually, i suspect the more rapid absorption and degradation with
> oral administration to make use via this route more predictable. i
> have just about given up vaginal use in favor of oral because my
> clinical observation suggested more rapid onset and more
> predictability.
> --
> James E. Sumners
> 1-800-404-3855
> http://www.cpdx.com
> http://www.datadirect.net

I agree with Dr. Sumners. We have been very happy with using misoprostol orally (about 40 patients in our practice so far), especially since that route makes it usable and effective in PROM, etc. We HOPE the future lies in using in PO use at home (in patients who have a neg BPP and NST, etc.) Cliff Goodman Private practice Chandler AZ





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