Re: Turner's mosaic/thrombocytopenia

From: John G. M. Robertson MD (jgmr@unixg.ubc.ca)
Wed Jun 4 18:26:57 1997


No experience in this area, but wouldn't depo-provera work well for her?

J.G.M.Robertson MD, 109-9181 Main St. Chilliwack, B.C. V2P 4M9 (604) 793-9988 e-mail jgmr@unixg.ubc.ca The best we can do for one another is to exchange our thoughts freely; and that, after all, is about all. James A. Froude (1818-1894)

On Wed, 4 Jun 1997, Laurie Lovely wrote:

> Dear Listers,
> I am now seeing an obese 14-year-old girl with short stature who was
> diagnosed with 46XX/45X karyotype ...
> The problem is that she has begun to have vaginal bleeding. Her
> gonadotropins are currently in the normal range with normal estradiol,
> so I believe she is having ovarian function. A transabdominal
> ultrasound during an episode of her bleeding showed an endometrial
> stripe of 3 mm. She has been taking continuous oral contraceptives for
> 2-1/2 months but has continued to have sporadic episodes of bleeding,
> usually correlated with platelet nadirs. Since she has a
> high-maintenance medication regimen already (growth hormone, insulin), I
> would like to keep her meds as simple as possible (i.e., avoid monthly
> Depot-Lupron with add-back therapy). If anyone has experience in
> managing a related problem, I would love to hear suggestions. This
> patient, her mother, and I thank you in advance.
>
> --
> Laurie Lovely, MD
> RE fellow, UNC-Chapel Hill
>





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