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Re: Mitral Valve ProlapseFrom: Harvey S. Marchbein, M.D. (hmarchbein@worldnet.att.net)Wed May 28 09:27:38 1997
At Wed, 28 May 1997, DoctorJoe@aol.com wrote: > ><<>Over here to the indications for antibiotic prohylaxis are: >>1 Women with mechanical valve replacements >>2 Women with past history of endocarditis. > >-- >>Malcolm Griffiths > >We add patients who are symptomatic with MVP and patients with mitral >regurgitation. > >-- >Harvey>> > >As I understand the theory behind it, a purist would give prophylaxis to >anyone with a significant MURMUR, but not simply a CLICK alone. Supposedly >it's the turbulence of the blood flow which causes a relative area of low >pressure that is somewhat "protected" from the body's immune system, allowing >for bacteria to settle out and grow without disturbance. In theory, I agree. But in practical terms, those in which an increased chance of SBE exists, the ?American Heart Association about January1991 (sorry, Bob, I don't have the reference. I'm on vacation!) recommended no prophylaxis for ob-gyn procedures unless antibiotics would be used without the diagnosis of MVP, e.g. infection, temperature elevation, prolonged labor. It is the opinion of the cardiologists in our geographic area that mitral regurgitation indicates a greater functional abnormality of the valve, increasing the likelihood of infection. Similarly, symptomatology is more likely to be related to greater functional abnormality of the valve and therefore, these two criteria will increase the risk of SBE (although the MR is considered much more of a risk than the symptom expression).
-- Harvey
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