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Re: factor XI From: Edmund F. Funai, MD (funaie@is4.nyu.edu) Tue Apr 29 11:12:52 1997 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: cerny.eliz: "Re: 63 year old mom" Previous message: FlynnCNM@aol.com: "Re: 63 years old and pregnant" In reply to: Margaret Lipton CNM: "Re: episiotomy and shoulder dystocia wasits effects on perineal" Next in thread: Laurie Lovely: "Re: episiotomy and shoulder dystocia wasits effects on perineal body/external anal sphinctor" At Sun, 27 Apr 1997, Allen Gardner wrote: > >Greetings, >Do you make any changes in routine anaesthetesia/delivery >for a healthy woman with coagulation factor XI deficiency? >Thanks. >Allen > >-- >Allen Gardner MD, Genetics >Oshawa General Hospital >Oshawa, Ontario, L1G 2B9, Canada > -- Like you so often hear...it depends. Factor XI deficiency is most commonly found in Ashkenazi and Bedouins. Recently it has been shown that those with bleeding diathesis (many people with XI deficiency are asymptomatic) also have platelet disorders. The treatment of choice in those patients with prior bleeding problems seems to be desmopressin. Without a history of problems I would do a bleeding time before any treatment. If for some reason desmopressin is needed and not available, fresh frozen plasma may be used. Cryoprecipitate is a poor choice, because it only replaces fibrinogen and factor VIII/ Good Luck. EF Funai NYU Medical Center Division of Maternal-Fetal Medicine Next message: cerny.eliz: "Re: 63 year old mom" Previous message: FlynnCNM@aol.com: "Re: 63 years old and pregnant" In reply to: Margaret Lipton CNM: "Re: episiotomy and shoulder dystocia wasits effects on perineal" Next in thread: Laurie Lovely: "Re: episiotomy and shoulder dystocia wasits effects on perineal body/external anal sphinctor"

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