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Re: HRT dosing variationsFrom: Larry Glazerman (glazerman@enter.net)Mon Mar 31 16:21:08 1997
>In message <199703290622.AAA21872@talk.obgyn.net> writes: >> 50 yo W female, smoker, rheumatoid arthritis, states progesterone >> component of her HRT makes her depressed. No menses for 4 yrs. Previous >> concomitant estrogen-progestin had been reduced to progestin on days >> 1-14. Is she a possible candidate for progestins every third month or >> might micronized progestin help? Thank you. > >Let me extend this a bit, to a hypothetical. Assume that we've tried every >form >of progestin, and none can be tolerated. Do you continue to prescribe the >estrogen? Her smoking gives her two reasons to need it even more than a >non-smoker (heart disease and osteoporosis), and the absolute risk of >endometrial Ca induced by unopposed estrogen is small (though the relative >risk >is substantial). If you do proceed with estrogen, do you recommend >hysterectomy >first? Endometrial ablation? > >--------------------------------------------------------------------------- > >--------------------------------------------------------------------------- > >--------------------------------------------------------------------------- >Bob Woolley >St. Paul, Minnesota > >"It's just a little cough." > > --Mimi, in Puccini's "La Boheme," Act IV > (about 10 minutes before dying of tuberculosis) I have some patients like this on estrogen alone. I do endo biopsy and TV Ultrasound yarrly
-- Larry R. Glazerman, M.D. FACOG Valley Ob-Gyn Associates Allentown PA
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