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Re: very low alfafetoprotein levelFrom: AFPPLUS3@aol.comWed Mar 12 06:56:35 1997
In a message dated 97-03-11 18:05:31 EST, you write: << I would like your oppinions about this case: 32 years old primigravida with low levels of maternal serum AFP. After counselled she decided to have an amnio. Result: normal karyotype, but the amniotic fluid alfafetoprotein level is 2,5 ngrm/ml at 17 weeks (normal= 11,5 ngrm/ml). The scan at 20 weeks showed no abnormality. What can be the cause for this very low AFP level. Thank you
>> The event you write about has many possiblities, one possibility is congenital absence of AFP. I know of 2 cases in the literature, and we are presently following one case now, similar to yours. If you would like, please write me and I will send you the references. The two cases which I reference had a "normal" outcome. Leonard H. Kellner,MS Administrative Director, Laboratory Services, Reproductive Genetics Laboratory Dept. of Obstetrics and Gynecology Montefiore Medical Center - Albert Einstein College of Medicine 718-405-8100
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