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Re: Abnormal Triple Screen & AFP From: Malcolm Griffiths (malcolm@mgriff22.demon.co.uk) Sat Mar 8 09:34:27 1997 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Malcolm Griffiths: "Re: x-ray pelvimetry" Previous message: Malcolm Griffiths: "Finnish Nephrotic syndrome ( was Abnormal Triple ... )" In reply to: Dr. Michael Hunter: "Abnormal Triple Screen & AFP" In message <1.5.4.32.19970303223240.00696844@mail.obgyn.net>, "Dr. Michael Hunter" <mike@sccsi.com> writes >Have a patient with intrauterine fetal demise at 16-17 weeks gestation. She >had an abnormal Trisomy screen and an elevated AFP and was sent for >evaluation with level II ultrasound and amniocentesis. A normal karyotype >was noted and a normal ultrasound except for a low amniotic fluid volume. > >One week later the patient presented with no fetal heart motion and had a >prostaglandin induction. The path report of the fetus and placenta was normal. > >My question is there any reports or studies concerning the outcome of >patients with abnormal trisomy screen and elevated AFP? How does one >counsel these patients and how to monitor? If both AFP and BHCG are raised there should be a high expectation of current or imminent fetal demise. These values may also be associated with other trisomies and triploidy. If they don't experience IUFD and chromosomes are normal then watch like a hawk for pre-eclampsia, APH, IUGR and everything else. Hope whoever did the amnio told her an IUFD was likely even without the amnio and she's not blaming the amnio for the death ! Malcolm Griffiths MD,MRCOG,MFFP,Cert.Mgmnt Obstetrician & Gynaecologist Luton & Dunstable Hosp., LU6 2DT, UK. Tel: 01582-497459 (office) Fax: 01582-497424 01525-222849 (home) email: Malcolm@mgriff22.demon.co.uk http://www.obgyn.net/board/griffith.htm "It is dangerous to be right on a subject on which the established authorities are wrong." (Voltaire) "But sometimes it's fun :-)" (Griffiths) Next message: Malcolm Griffiths: "Re: x-ray pelvimetry" Previous message: Malcolm Griffiths: "Finnish Nephrotic syndrome ( was Abnormal Triple ... )" In reply to: Dr. Michael Hunter: "Abnormal Triple Screen & AFP"

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