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Re: abnl triple screenFrom: ATB28@aol.comFri Mar 7 06:46:45 1997
In a message dated 97-03-06 21:02:20 EST, rbraun@indyunix.iupui.edu writes:
<< The AFP alone will pick up about 50% and Maternal age alone will be around
25%.
>> Actually, using maternal age > 34 years as a screening test will result in the detection of only about *20%* of fetal Down syndrome; MSAFP increases detection my about another *15%*. The best predictor, in a triple test, is the hCG component; estriol is most effective as a Dowwn syndrome markerin younger women (see Haddow NEJM paper) and in detecting other aneuploidies such as Edwards syndrome (T-18). Allan
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