Re: abnl triple screen

From: rbraun@indyunix.iupui.edu
Thu Mar 6 19:54:49 1997


What do you mean by False Positive?. The triple screen gives a result as a 1/X chance of having Down'sSyndrome. If you rec. amniocentesis and all patients accept it when the risk is greater than 1/365, you will diagnose about 2/3 fo the Down's syndrome patients in your population. The AFP alone will pick up about 50% and Maternal age alone will be around 25%. The triple screen should never be reported to the patient as normal or abnormal. They should be told the risk is 1 in ten thousand or the risk is one in ten.

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On Wed, 5 Mar 1997 Snorklesue@aol.com wrote:

> Dear List, > Since we're talking about triple screen, what do you quote your pts as false > positive rate of triple screen for Down's syndrome? Are there references to > this? > > Susan Lee, MD > Womack Army MedCen >





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